Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn +3 more
doaj +1 more source
The Receptor-Like Kinase SERK3/BAK1 Is Required for Basal Resistance against the Late Blight Pathogen Phytophthora infestans in Nicotiana benthamiana [PDF]
BACKGROUND The filamentous oomycete plant pathogen Phytophthora infestans causes late blight, an economically important disease, on members of the nightshade family (Solanaceae), such as the crop plants potato and tomato.
Chaparro-Garcia, Angela +8 more
core +1 more source
Enhancing crop innate immunity: new promising trends
Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment. Due to the activation of the pattern-triggered immunity (PTI) response that largely relies on accurate detection of pathogen- or microbe-associated
Pin-Yao eHuang, Laurent eZimmerli
doaj +1 more source
Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei
DNA damage-induced micronuclei are linked to downstream viral signalling through the cGAS pattern recognition receptor. Here, the authors identify features of micronuclei chromatin that determine cGAS-MN recruitment and associated pathway activation.
Kate M. MacDonald +5 more
doaj +1 more source
Pattern‐recognition receptors in human eosinophils [PDF]
SummaryThe pattern‐recognition receptor (PRR) family includes Toll‐like receptors (TLRs), nucleotide‐binding oligomerization domain (NOD) ‐like receptors (NLRs), RIG‐I‐like receptors (RLRs), C‐type lectin receptors (CLRs) and the receptor for advanced glycation end products (RAGE).
Anne Månsson, Kvarnhammar +1 more
openaire +2 more sources
CLEC5A is a critical receptor in innate immunity against Listeria infection
The lectin receptor CLEC5A is a pattern recognition receptor that has been shown to detect dengue and Japanese encephalitis virus. Here the authors show that CLEC5A is needed for optimal ROS production, NET formation and other immune responses to ...
Szu-Ting Chen +10 more
doaj +1 more source
TLR-9 Expression in Human Bronchial Epithelial Cells induced with Lipopolysaccharide [PDF]
The study conducted here was to investigate the gene and protein expression of Toll like receptor 9 when human bronchial epithelial cells were induced by lipopolysaccharide.
Sangeetha Dharmalingam +1 more
core +1 more source
Tiling solutions for optimal biological sensing [PDF]
Biological systems, from cells to organisms, must respond to the ever changing environment in order to survive and function. This is not a simple task given the often random nature of the signals they receive, as well as the intrinsically stochastic ...
Walczak, Aleksandra M.
core +2 more sources
Advances in Plant-Nematode Interactions with Emphasis on the Notorious Nematode Genus Meloidogyne. [PDF]
Plant infections by plant-parasitic nematodes (PPNs) continue to be one of the major limitations in agricultural systems. Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are one of the most important groups of PPNs worldwide.
Kaloshian, Isgouhi, Teixeira, Marcella
core
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources

