Results 51 to 60 of about 689,097 (325)

Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair

Cell Reports, 2017
Receptor interacting protein kinase 3 (RIPK3) induces necroptosis, a type of regulated necrosis, through its kinase domain and receptor interacting protein (RIP) homotypic interaction motif (RHIM).
Kenta Moriwaki, Sakthi Balaji, John Bertin, Peter J. Gough, Francis Ka-Ming Chan   +4 more
doaj   +1 more source

Galectin-1 from redlip mullet Liza haematocheilia: identification, immune responses, and functional characterization as pattern recognition receptors (PRRs) in host immune defense system

Fisheries and Aquatic Sciences, 2022
Galectins, a family of β-galactoside-binding lectins, have emerged as soluble mediators in infected cells and pattern recognition receptors (PRRs) responsible for evoking and regulating innate immunity.
Chaehyeon Lim, Hyukjae Kwon, Jehee Lee
doaj   +1 more source

Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]

, 2011
The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Brown, MW, Warburton, E Clea, Endean, E. P. E., Fontaine-Palmer, N. S., Chris J. Tinsley, Endean, Emma P E, Aggleton, John P, Tinsley, CJ, John P. Aggleton, Emma P.E. Endean, Vincent, Maria, Aggleton, John Patrick, Endean, EPE, Maria Vincent, E. Clea Warburton, Nadine S. Fontaine-Palmer, Brown, M. W., Malcolm W. Brown, Tinsley, Chris J, Brown, Malcolm W, Vincent, M., Fontaine-Palmer, NS, Tinsley, C. J., Vincent, M, Fontaine-Palmer, Nadine S, Aggleton, JP, Warburton, EC, Warburton, E. C.   +27 more
core   +1 more source

MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage

Cell Reports, 2016
Microvascular endothelial cells maintain a tight barrier to prevent passage of plasma and circulating immune cells into the extravascular tissue compartment, yet endothelial cells respond rapidly to vasoactive substances, including thrombin, allowing ...
Linda R. Klei, Dong Hu, Robert Panek, Danielle N. Alfano, Rachel E. Bridwell, Kelly M. Bailey, Katherine I. Oravecz-Wilson, Vincent J. Concel, Emily M. Hess, Matthew Van Beek, Phillip C. Delekta, Shufang Gu, Simon C. Watkins, Adrian T. Ting, Peter J. Gough, Kevin P. Foley, John Bertin, Linda M. McAllister-Lucas, Peter C. Lucas   +18 more
doaj   +1 more source

VSTM1/SIRL-1: An Inhibitory Pattern Recognition Receptor Regulating Myeloid Cells. [PDF]

Eur J Immunol
Innate immune cells express a plethora of inhibitory receptors, many of which recognize molecular patterns. An appropriate balance between signaling via activating and inhibitory pattern recognition receptors is important for a proper immune response ...
Koops M, Meyaard L.
europepmc   +2 more sources

Identification of receptor complex components and receptor activation mechanisms in plant innate immunity [PDF]

, 2011
Plants rely on an innate immune system which successfully recognizes and restricts pathogenic microbes. The key for this defense is the detection of pathogen derived non-self signatures and endogenous elicitors released during a microbial attack.
Mentzel, Tobias
core   +1 more source

The role of BRI1-associated kinase 1 (BAK1) in the regulation of plant innate immunity : functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana [PDF]

, 2014
The role of BRI1-ASSOCIATED KINASE 1 (BAK1) in the regulation of plant innate immunity: functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana SUMMARY BAK1 (BRI1-ASSOCIATED KINASE 1) is an intensively studied member ...
Kiss-Papp, Márta
core   +1 more source

A Bacterial Tyrosine Phosphatase Inhibits Plant Pattern Recognition Receptor Activation

Science, 2014
Innate immunity relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) located on the host cell's surface. Many plant PRRs are kinases. Here, we report that the Arabidopsis receptor kinase EF-TU
A. Macho, B. Schwessinger, Vardis Ntoukakis, Alexandre Brutus, C. Segonzac, Sonali Roy, Y. Kadota, M. Oh, J. Skłenar, P. Derbyshire, Rosa Lozano-Durán, F. G. Malinovsky, Jacqueline Monaghan, Frank L. H. Menke, S. Huber, S. He, C. Zipfel   +16 more
semanticscholar   +3 more sources

CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond

Advances in Experimental Medicine and Biology, 2020
CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans.
Pei-Shan Sung, Wei-Chiao Chang, S. Hsieh
semanticscholar   +1 more source

Pattern recognition receptors in microbial keratitis [PDF]

Eye, 2015
Microbial keratitis is a significant cause of global visual impairment and blindness. Corneal infection can be caused by a wide variety of pathogens, each of which exhibits a range of mechanisms by which the immune system is activated. The complexity of the immune response to corneal infection is only now beginning to be elucidated.
Taube, M.A., Del Mar Cendra, M., Elsahn, A., Christodoulides, Myron, Hossain, Parwez   +4 more
openaire   +3 more sources