Results 51 to 60 of about 246,063 (155)

Enhancing crop innate immunity: new promising trends

Frontiers in Plant Science, 2014
Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment. Due to the activation of the pattern-triggered immunity (PTI) response that largely relies on accurate detection of pathogen- or microbe-associated
Pin-Yao eHuang, Laurent eZimmerli
doaj   +1 more source

A NOVEL MULTI-EPITOPE PEPTIDE VACCINE CONSTRUCT AGAINST INFLUENZA A VIRUS AND STREPTOCOCCUS PNEUMONIAE CO-INFECTION: AN IN SILICO APPROACH

NUST Journal of Natural Sciences, 2020
Viral and bacterial respiratory tract co-infections in the same host often result in severity and heightened pathology of illness compared to single infections.
Maha Kaiser, Amjad Ali
doaj   +1 more source

Effect of human breast milk on innate immune response: Up-regulation of bacterial pattern recognition receptors and innate cytokines in THP-1 monocytic cells

European Journal of Inflammation, 2021
Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn, Soon Young Shin, Jun Hwan Song, Nam Mi Kang   +3 more
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Immunodeficiency and Genetic Defects of Pattern-Recognition Receptors [PDF]

New England Journal of Medicine, 2011
This review gives an account of genetic defects of the innate immune system with clinical relevance. Susceptibility to infection in association with defective innate immunity is usually confined to particular classes of organisms (e.g., flagellated bacteria).
Netea, M.G., Meer, J.W.M. van der
openaire   +4 more sources

Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei

Nature Communications, 2023
DNA damage-induced micronuclei are linked to downstream viral signalling through the cGAS pattern recognition receptor. Here, the authors identify features of micronuclei chromatin that determine cGAS-MN recruitment and associated pathway activation.
Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, Sarika Khasnis, Cheryl H. Arrowsmith, Shane M. Harding   +5 more
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CLEC5A is a critical receptor in innate immunity against Listeria infection

Nature Communications, 2017
The lectin receptor CLEC5A is a pattern recognition receptor that has been shown to detect dengue and Japanese encephalitis virus. Here the authors show that CLEC5A is needed for optimal ROS production, NET formation and other immune responses to ...
Szu-Ting Chen, Fei-Ju Li, Tzy-yun Hsu, Shu-Mei Liang, Yi-Chen Yeh, Wen-Yu Liao, Teh-Ying Chou, Nien-Jun Chen, Michael Hsiao, Wen-Bin Yang, Shie-Liang Hsieh   +10 more
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Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Showed Cardioprotection Effect in a Myocardial Ischemia (MI) Mouse Model

Proceedings, 2019
TLR4, a member of the toll-like receptors (TLRs) family, serves as a pattern recognition receptor in the innate immune response to different microbial pathogens. [...]
Lena Trifonov, Vadim Nudelman, Michael Zhenin, Guy Cohen, Krzysztof Jozwiak, Edward Korshin, Hanoch Senderowitz, Asher Shainberg, Edith Hochhauser, Arie Gruzman   +9 more
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Vitellogenin functions as a multivalent pattern recognition receptor with an opsonic activity. [PDF]

PLoS ONE, 2008
BACKGROUND: Vitellogenin (Vg), a major reproductive protein, has been associated with infection-resistant response in fish. However, the underlying mechanisms by which Vg is involved in anti-infectious response are not understood. METHODOLOGY/RESULTS: By
Zhaojie Li, Shicui Zhang, Qinghui Liu
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Editorial: Pattern Recognition Receptors and Cancer

Frontiers in Immunology, 2015
The problem of cancer remains one of the most immense challenges to current biomedical research. Affecting populations in all countries and all regions, this disease is responsible for millions of deaths annually (1). Evasion of the immune system is an ominous feature of cancers, which often leads to tumor outgrowth, epithelial–mesenchymal transition ...
Kutikhin, Anton G., Yuzhalin, Arseniy E.
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Pattern recognition receptors in fungal immunity

Seminars in Cell & Developmental Biology, 2019
Over the last decade, invasive fungal infections have emerged as a growing threat to human health worldwide and novel treatment strategies are urgently needed. In this context, investigations into host-pathogen interactions represent an important and promising field of research.
Patin, Emmanuel C., Thompson, Aiysha, Orr, Selinda J.   +2 more
openaire   +2 more sources