Results 61 to 70 of about 246,063 (155)

TREM1—Microglia crosstalk: Neurocognitive disorders

Brain Research Bulletin
Neurocognitive Disorders (NCDs) primarily affect cognitive functions, including learning, memory, perception, and problem-solving. They predominantly arise as pathological sequelae of central nervous system (CNS) disorders.
Huashan Li, Wanqiu Yu, Xue Zheng, Zhaoqiong Zhu   +3 more
doaj   +1 more source

Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus

Frontiers in Immunology, 2017
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modulated
Luisa C. Carneiro, Luisa C. Carneiro, Carmen Bedford, Sarah Jacca, Sarah Jacca, Alfonso Rosamilia, Alfonso Rosamilia, Vera F. de Lima, Gaetano Donofrio, I. Martin Sheldon, James G. Cronin   +10 more
doaj   +1 more source

Pattern-recognition receptors and recognition of pathogens

Journal of Medicine and Life Science, 2009
The mammalian host has evolved innate immune strategies to detect and respond to rapidly to diverse group of microorganisms. Microbial recognition is achieved by pattern-recognition receptors (PRRs) such as toll-like receptors (TLRs) and Nod-like receptor (NLRs).
openaire   +1 more source

Comparative genome analysis reveals an absence of leucine-rich repeat pattern-recognition receptor proteins in the kingdom Fungi.

PLoS ONE, 2010
BackgroundIn plants and animals innate immunity is the first line of defence against attack by microbial pathogens. Specific molecular features of bacteria and fungi are recognised by pattern recognition receptors that have extracellular domains ...
Darren M Soanes, Nicholas J Talbot
doaj   +1 more source

Type I interferon and pattern recognition receptor signaling following particulate matter inhalation

Particle and Fibre Toxicology, 2012
Background Welding, a process that generates an aerosol containing gases and metal-rich particulates, induces adverse physiological effects including inflammation, immunosuppression and cardiovascular dysfunction.
Erdely Aaron, Antonini James M, Salmen-Muniz Rebecca, Liston Angie, Hulderman Tracy, Simeonova Petia P, Kashon Michael L, Li Shengqiao, Gu Ja K, Stone Samuel, Chen Bean T, Frazer David G, Zeidler-Erdely Patti C   +12 more
doaj   +1 more source

Pattern Recognition Receptors: From the Cell Surface to Intracellular Dynamics

Molecular Plant-Microbe Interactions, 2007
Detection of potentially infectious microorganisms is essential for plant immunity. Microbial communities growing on plant surfaces are constantly monitored according to their conserved microbe-associated molecular patterns (MAMPs).
Denise Altenbach, Silke Robatzek
doaj   +1 more source

ER-mediated control for abundance, quality, and signaling of transmembrane immune receptors in plants

Frontiers in Plant Science, 2014
Plants recognize a wide range of microbes with cell-surface and intracellular immune receptors. Transmembrane pattern recognition receptors (PRRs) initiate immune responses upon recognition of cognate ligands characteristic of microbes or aberrant ...
Nico eTintor, Yusuke eSaijo
doaj   +1 more source

Role of toll-like receptors in pulmonary immunity: mechanisms and therapeutic implications

Frontiers in Immunology
Toll-like receptors (TLRs) belong to the family of pattern recognition receptors (PRRs), playing critical roles in linking innate with adaptive immunity by recognizing pathogen-associated molecular patterns (PAMPs) and danger-associated molecular ...
Zhuojian Qu, Zhiliang Guo, Chunjuan Yang, Xiumei Guan, Min Cheng, Pingping Wang, Donghua Xu, Donghua Xu   +7 more
doaj   +1 more source

Pattern Recognition Receptors in Drosophila

, 2003
The foundation of the innate immune system is the recognition of infectious non-self. Janeway (1,2) has proposed that this recognition is mediated by the binding of host pattern recognition proteins to pathogen-associated molecular patterns (PAMPs). PAMPs were originally defined as structures found on the surfaces of microorganisms but not present on ...
Mika Rämet, Alan Pearson, Kati Baksa, Asha Harikrishnan   +3 more
openaire   +1 more source

β-sheet stabilization of the island domain underlies ligand-induced LRR-RP activation of plant immune signaling

Nature Communications
Leucine-rich repeat (LRR) receptor kinases (RKs) and receptor proteins (RPs) are important classes of plant pattern recognition receptors (PRRs) activating pattern-triggered immunity.
Simon Snoeck, Lisha Zhang, Valentin Studer, Gijeong Kim, Álvaro D. Fernández-Fernández, Thorsten Nürnberger, Cyril Zipfel   +6 more
doaj   +1 more source