Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek +5 more
doaj +1 more source
Virus sensing receptors in cellular infectivity of influenza A virus
An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV).
Shaihana Almatrrouk +4 more
doaj +1 more source
Primary immunodeficiencies of pattern recognition receptors [PDF]
AbstractPrimary immunodeficiencies (PIDs) are severe defects in the capacity of the host to mount a proper immune response, and are characterized by an increased susceptibility to infections. Although classical immunodeficiencies have been characterized based on broad defects in cell populations (e.g.
Netea, M.G. +2 more
openaire +3 more sources
Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1
RIPK1 and RIPK3, two closely related RIPK family members, have emerged as important regulators of pathologic cell death and inflammation. In the current work, we report that the Bcr-Abl inhibitor and anti-leukemia agent ponatinib is also a first-in-class
Malek Najjar +13 more
doaj +1 more source
Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System
During acute bacterial meningitis, recognition of the bacterial envelope by immune cells of the central nervous system (CNS) generates a robust response that is essential to clear bacteria.
William J. MacCain, Elaine I. Tuomanen
doaj +1 more source
Feature learning via partial differential equation with applications to face recognition
Feature learning is a critical step in pattern recognition, such as image classification. However, most of the existing methods cannot extract features that are discriminative and at the same time invariant under some transforms.
Fang, Cong +7 more
core +1 more source
Informative shape representations for human action recognition
Shape and kinematics are two important cues in human movement analysis. Due to real difficulties in extracting kinematics from videos accurately, this paper proposes to address the problem of human action recognition by spatiotemporal shape analysis ...
Liang Wang +3 more
core +1 more source
Human motion recognition using gaussian processes classification
This paper investigates the applicability of Gaussian processes (GP) classification for recognition of articulated and deformable human motions from image sequences.
Liang Wang +5 more
core +1 more source
Plant pattern-recognition receptors
Plants are constantly exposed to would-be pathogens in their immediate environment. Yet, despite relying on innate immunity only, plants are resistant to most microbes. They employ pattern-recognition receptors (PRRs) for sensitive and rapid detection of the potential danger caused by microbes and pests. Plant PRRs are either surface-localized receptor
openaire +4 more sources
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
TNF mediated inflammation is critical in autoimmune mediated pathology, however many patients are refractory to current anti-TNF therapeutics. Here the authors show induction of several death ligands, in addition to TNF is sufficient to cause fatal ...
Lucia Taraborrelli +19 more
doaj +1 more source

