Results 81 to 90 of about 861,453 (229)

Vitellogenin functions as a multivalent pattern recognition receptor with an opsonic activity. [PDF]

PLoS ONE, 2008
BACKGROUND: Vitellogenin (Vg), a major reproductive protein, has been associated with infection-resistant response in fish. However, the underlying mechanisms by which Vg is involved in anti-infectious response are not understood. METHODOLOGY/RESULTS: By
Zhaojie Li, Shicui Zhang, Qinghui Liu
doaj   +1 more source

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

Journal of Experimental Medicine, 2016
Cerutti and collaborators show that the humoral arms of the innate and adaptive immune systems are functionally interconnected by pentraxin 3, a soluble pattern recognition receptor that couples innate immune recognition with antibody-inducing function.
Alejo Chorny, S. Casas-Recasens, J. Sintes, Meimei Shan, N. Polentarutti, R. García-Escudero, A. C. Walland, John R Yeiser, L. Cassis, J. Carrillo, Irene Puga, C. Cunha, C. Cunha, H. Bastos, H. Bastos, H. Bastos, Fernando Rodrigues, Fernando Rodrigues, J. Lacerda, António Morais, R. Dieguez‐Gonzalez, P. Heeger, G. Salvatori, A. Carvalho, A. Carvalho, A. García-Sastre, J. Blander, A. Mantovani, C. Garlanda, A. Cerutti   +29 more
semanticscholar   +1 more source

Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Showed Cardioprotection Effect in a Myocardial Ischemia (MI) Mouse Model

Proceedings, 2019
TLR4, a member of the toll-like receptors (TLRs) family, serves as a pattern recognition receptor in the innate immune response to different microbial pathogens. [...]
Lena Trifonov, Vadim Nudelman, Michael Zhenin, Guy Cohen, Krzysztof Jozwiak, Edward Korshin, Hanoch Senderowitz, Asher Shainberg, Edith Hochhauser, Arie Gruzman   +9 more
doaj   +1 more source

Eggplant and related species are promising genetic resources to dissect the plant immune response to Pseudomonas syringae and Xanthomonas euvesicatoria and to identify new resistance determinants [PDF]

, 2014
The apparent lack of durability of many resistance (R) genes highlights the need for the constant identification of new genetic sources of resistance for the breeding of new disease-resistant crop cultivars.
Clarke, Christopher R., Hayes, Byron W., Runde, Brendan J., Vinatzer, Boris A., Wicker, Emmanuel   +4 more
core   +1 more source

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]

, 2012
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone, Rajalingam, Krishnaraj, Dikic, Ivan   +2 more
core   +1 more source

Pattern Recognition Receptors and Infectious Diseases [PDF]

, 2012
Our bodies are under constant attack from pathogens. Despite this continual bombardment, under normal circumstances we remain healthy for most of our lives. This protection against infectious and harmful agents is provided by our immune system. The immune system can be broken into two elements: adaptive immunity and innate immunity.
Jopeace, Ardi Liaunardy, Howard, Chris B., Murton, Ben L., Edwards, Alexander D., Monie, Tom P.   +4 more
openaire   +3 more sources

Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent*

Journal of Biological Chemistry, 2016
The recognition of pathogen surface polysaccharides by glycan-binding proteins is a cornerstone of innate host defense. Many members of the C-type lectin receptor family serve as pattern recognition receptors facilitating pathogen uptake, antigen ...
Jonas Hanske, J. Schulze, Jonas Aretz, Ryan McBride, B. Loll, Henrik Schmidt, Y. Knirel, W. Rabsch, M. Wahl, J. Paulson, C. Rademacher   +10 more
semanticscholar   +1 more source

Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]

, 1998
The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
core   +2 more sources

TREM1—Microglia crosstalk: Neurocognitive disorders

Brain Research Bulletin
Neurocognitive Disorders (NCDs) primarily affect cognitive functions, including learning, memory, perception, and problem-solving. They predominantly arise as pathological sequelae of central nervous system (CNS) disorders.
Huashan Li, Wanqiu Yu, Xue Zheng, Zhaoqiong Zhu   +3 more
doaj   +1 more source

Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis. [PDF]

PLoS ONE, 2015
Understanding the molecular components of immune recognition of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, can help designing novel strategies to combat TB.
Anthony Troegeler, Geanncarlo Lugo-Villarino, Søren Hansen, Voahangy Rasolofo, Maiken Lumby Henriksen, Kenichiro Mori, Katsuki Ohtani, Carine Duval, Ingrid Mercier, Alan Bénard, Jérome Nigou, Denis Hudrisier, Nobutaka Wakamiya, Olivier Neyrolles   +13 more
doaj   +1 more source