Results 71 to 80 of about 19,461 (219)

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

The emerging roles of ribosome biogenesis in craniofacial development. [PDF]

, 2014
Neural crest cells (NCCs) are a transient, migratory cell population, which originates during neurulation at the neural folds and contributes to the majority of tissues, including the mesenchymal structures of the craniofacial skeleton.
Ross, Adam P, Zarbalis, Konstantinos S
core   +2 more sources

Vertical Growth of Facial Soft Tissues: A Longitudinal Three‐Dimensional Facial Growth Study

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective This longitudinal cohort study aimed to assess changes in vertical facial landmarks in individuals aged 10 to 18 years and identify sex differences in growth patterns. Materials and Methods One hundred and one individuals (males, n = 56; females, n = 45) were observed.
Signe Silinevica, Amir Nassereldine, Gundega Jakobsone, Jinjun Xiong   +3 more
wiley   +1 more source

PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis

eLife, 2018
Alveolar rhabdomyosarcoma is a pediatric soft-tissue sarcoma caused by PAX3/7-FOXO1 fusion oncogenes and is characterized by impaired skeletal muscle development. We developed human PAX3-FOXO1 -driven zebrafish models of tumorigenesis and found that PAX3-
Genevieve C Kendall, Sarah Watson, Lin Xu, Collette A LaVigne, Whitney Murchison, Dinesh Rakheja, Stephen X Skapek, Franck Tirode, Olivier Delattre, James F Amatruda   +9 more
doaj   +1 more source

The regenerative potential of Pax3/Pax7 on skeletal muscle injury

Journal of Genetic Engineering and Biotechnology, 2022
Background Skeletal muscle mishaps are the most well-known incidents in society, especially among athletes and the military population. From the various urgency, this accident needs to be cured more quickly.
Muhamad Azhar, Bantari Wisynu Kusuma Wardhani, Editha Renesteen   +2 more
doaj   +1 more source

Crizotinib-induced antitumour activity in human alveolar rhabdomyosarcoma cells is not solely dependent on ALK and MET inhibition [PDF]

, 2015
BACKGROUND: Rhabdomyosarcoma (RMS) is the most commonly diagnosed malignant soft tissue tumour in children and adolescents. Aberrant expression of Anaplastic Lymphoma Kinase (ALK) and MET gene has been implicated in the malignant progression of RMS ...
CAMERO, SIMONA, CECCARELLI, SIMONA, CLERICO, Anna, DOMINICI, Carlo, Losty, Paul D, Mannarino, Olga, Mcdowell, Heather P, MEGIORNI, Francesca, PAIANO, MILENA, Pizer, Barry, PIZZUTI, Antonio, Shukla, Rajeev   +11 more
core   +1 more source

Biphenotypic sinonasal sarcoma with PAX3/FOXO1 fusion

Polish Journal of Pathology, 2023
Biphenotypic sinonasal sarcoma (BSNS), previously known as low-grade sinonasal sarcoma, is a rare tumour of the sinonasal tract, first described in 2012. It involves both myogenic and neural differentiation and is characterized by PAX3 rearrangement.
Ilkay Tosun, Murat H. Karabulut, Ismail Yilmaz, Ahmet A. Cırık, Onur Sahin   +4 more
openaire   +3 more sources

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma [PDF]

Journal of Biological Chemistry, 2015
Metastatic melanoma is an aggressive and deadly disease. The chemokine receptor CXCR4 is active in melanoma metastasis, although the mechanism for the promotion and maintenance of CXCR4 expression in these cells is mostly unknown. Here, we find melanoma cells express two CXCR4 isoforms, the common version and a variant that is normally restricted to ...
Jennifer D, Kubic, Jason W, Lui, Elizabeth C, Little, Anton E, Ludvik, Sasank, Konda, Ravi, Salgia, Andrew E, Aplin, Deborah, Lang   +7 more
openaire   +2 more sources

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source