Results 21 to 30 of about 11,246 (181)
Stem Cell Research & Therapy, 2020 Background Pluripotent stem cells present the ability to self-renew and undergo differentiation into any cell type building an organism. Importantly, a lot of evidence on embryonic stem cell (ESC) differentiation comes from in vitro studies.
Anita Florkowska +8 more
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Czech Journal of Animal Science, 2021 Ubiquitin-specific protease 8 (USP8), a member of the ubiquitin-specific protease (USP) family, was originally identified as playing a role in the regulation of growth and cell cycle. However, its functional role in myogenesis is unknown.
Shaoyu Wang +6 more
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Biosensors, 2023 The principles of myogenesis play crucial roles in the production of cultured meat, and identifying protein stimulators associated with myogenesis holds great potential to enhance the efficiency of this process.
In-Sun Yu +6 more
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Human Umbilical Vein Endothelial Cells Express the DUX4 Protein: A Basis for Further Vascular Research [PDF]
Türk Patoloji DergisiObjective: A growing body of evidence suggests a correlation between endothelial cell dysfunction and cancer, as well as facioscapulohumeral dystrophy, both of which are DUX4-related diseases. However, the endogenous expression of DUX4 within endothelial
Ceren HANGUL +5 more
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Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero
Journal of Developmental Biology, 2022 Pax3 and Pax7 transcription factors are paralogs within the Pax gene family that that are expressed in early embryos in partially overlapping expression domains and have distinct functions.
Hong-Ming Zhou, Simon J. Conway
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The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor- Bearing BALB-C Mice [PDF]
Journal of Advanced Biomedical Sciences, 2019 Background & Objective: Many cancer patients suffer from cachexia or cancer-induced muscle atrophy. Cachexia can have various causes one of which is the reduction of muscle regeneration.
enayatollah Asadmanesh +4 more
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Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in-mouse line
Skeletal Muscle, 2018 Background Satellite cells are residential muscle stem cells that express a paired box protein, PAX7. Results Here, we report a knock-in mouse line expressing a PAX7-enhanced yellow fluorescent protein (YFP) fusion protein that enables visualization of ...
Yasuo Kitajima, Yusuke Ono
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A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR [PDF]
Proceedings of the National Academy of Sciences, 2006 Alveolar rhabdomyosarcoma (ARMS) is an aggressive myogenic-type tumor and a gain-of-function disease, caused by misexpression of the PAX3-FKHR or PAX7-FKHR fusion oncoprotein from structurally rearranged chromosomes. PAX3-FKHR misexpressed in terminally differentiating mouse myofibers can cause rhabdomyosarcoma at a low frequency ...
Rene L, Galindo +2 more
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A Postnatal Pax7+ Progenitor Gives Rise to Pituitary Adenomas [PDF]
Genes & Cancer, 2010 Pituitary adenomas are classified into functioning and nonfunctioning (silent) tumors on the basis of hormone secretion. However, the mechanism of tumorigenesis and the cell of origin for pituitary adenoma subtypes remain to be elucidated. Employing a tamoxifen-inducible mouse model, we demonstrate that a novel postnatal Pax7(+) progenitor cell ...
Tohru, Hosoyama +11 more
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Pax7 reporter mouse models: a pocket guide for satellite cell research
European Journal of Translational Myology, 2023 Since their discovery, satellite cells have showcased their need as primary contributors to skeletal muscle maintenance and repair. Satellite cells lay dormant, but when needed, activate, differentiate, fuse to fibres and self-renew, that has bestowed ...
Huascar Pedro Ortuste Quiroga +2 more
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