Results 101 to 110 of about 16,461 (203)

Optimering av immunhistokemisk infärgning för PAX8 med klon SP348

, 2020
Paired box protein - 8 (PAX8) är ett protein kodat av PAX8-genen som lokaliseras i kromosom 2. PAX8 reglerar transkriptionen för organogenesen av tyreoidea, placenta, njure samt innerörat.
Ekström, Emelie
core   +1 more source

A WT1-positive pleural neoplasm. Is it always a mesothelioma?

African Journal of Thoracic and Critical Care Medicine, 2023
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G Gaggero, D Taietti, M Concardi, M Mora
doaj  

Prognostic value of PAX8 in small cell lung cancer

Heliyon
Objectives: Small cell lung cancer (SCLC) shows poor prognosis since it metastasizes widely at early stage. Paired box gene (PAX) 8 is a transcriptional factor of PAX family, of which the expression in lung cancer is a controversial issue, and its ...
Fengyun Tao, Hangyan Zhu, Jiayun Xu, Yanan Guo, Xin Wang, Lei Shao, Deng Pan, Guosheng Li, Rong Fang   +8 more
doaj   +1 more source

Novel non-synonymous mutations of PAX8 in a cohort of Chinese with congenital hypothyroidism

Chinese Medical Journal, 2019
. Background:. The transcription factor paired box 8 (PAX8) was associated with type 2 congenital non-goitrous hypothyroidism (CHNG2), a clinical phenotype of congenital hypothyroidism (CH). Though studied in a few regions with different ethnicities, the
Fang Qian, Gui-Yu Li, Xiang-Jun Wu, Qin Jia, Guan-Ting Lyu, Man-Li Wang, Jun Wang, Xin Chen   +7 more
doaj   +1 more source

PAX8 Mutation Disturbing Thyroid Follicular Growth: A Case Report

, 2011
Context:Heterozygous inactivating PAX8 mutations cause congenital hypothyroidism. Although more than 30 mutation carriers have been reported, no histological examination of the thyroid has been conducted.Objective:The objective of this study was to ...
Yumi Asakura, Tomonobu Hasegawa, Koji Muroya, Ryuji Fukuzawa, Masanori Adachi, Satoshi Narumi, Akira Yoshida, Kaori Kameyama   +7 more
core   +1 more source

Diagnostic utility of PAX8 in differentiation of mullerian from non-mullerian tumors

Advanced Biomedical Research, 2014
Background: Considering the high prevalence of female genital tract neoplasms, non-specific nature of the initial symptoms, higher possibility of metastasis by the time of diagnosis, importance of differentiating metastatic Mullerian tumors or metastatic
Mitra Heidarpour, Zahra Tavanafar
doaj   +1 more source

First National Expanded Genomic Newborn Screening Program in Qatar; A Pilot Study, Doha‐Heidelberg Collaboration

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2374-2380, October 2026.
Reem Alsulaiman, Sarah Okashah, Radja Messai Badji, Fatemeh Abbaszadeh, Yaser Alsarraj, Rehab Ali Abdulrahman, Noora Shahbeck, Thalib Moideen, Reema El Hassan, Fatima Al‐Hamaydeh, Einas Alkuwari, Said Ismail, Hilal Al‐ Rifai, Ghassan Abdoh, Christian P. Schaaf, Georg Hoffmann, Saad Al‐Kaabi, Wadha Al‐Muftah, Tawfeg Ben‐Omran   +18 more
wiley   +1 more source

N-terminal PAX8 polyclonal antibody shows cross-reactivity with N-terminal region of PAX5 and is responsible for reports of PAX8 positivity in malignant lymphomas

, 2012
Recently, reports using immunohistochemistry and a polyclonal antibody directed against the N-terminal region of PAX8 describe PAX8 expression in malignant lymphomas.
Kranthi Kunkalla, Kunkalla, Kranthi, Vega, Francisco, L Jeffrey Medeiros, Francisco Vega, Medeiros, L Jeffrey, Michelle D Williams, Moretti, Lucas, Rajesh R Singh, Singh, Rajesh R, Williams, Michelle D, Lucas Moretti   +11 more
core   +1 more source

Diagnostic algorithm for determining primary tumor sites using peritoneal fluid.

PLoS ONE, 2018
This study was conducted to develop a novel algorithm for determining the origin of tumors by combining analysis of cluster patterns with immunocytochemistry (ICC) for markers in cells from fine-needle aspirates of ascites.
Cheol Keun Park, Douglas P Malinowski, Nam Hoon Cho   +2 more
doaj   +1 more source

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

Nature Communications, 2019
Transcription factor networks shape the gene expression programs responsible for normal cell identity and pathogenic state. Using Core Regulatory Circuitry analysis (CRC), we identify PAX8 as a candidate oncogene in Renal Cell Carcinoma (RCC) cells ...
Melusine Bleu, S. Gaulis, R. Lopes, K. Sprouffske, Verena Apfel, S. Holwerda, M. Pregnolato, Umut Yildiz, Valentina Cordo’, A. Dost, Judith Knehr, Walter Carbone, F. Lohmann, Charles Y. Lin, J. Bradner, A. Kauffmann, Luca Tordella, G. Roma, G. Galli   +18 more
semanticscholar   +1 more source