Results 61 to 70 of about 5,722 (164)

Screening for mutations in transcription factors in a Czech cohort of 170 patients with congenital and early-onset hypothyroidism: identification of a novel PAX8 mutation in dominantly inherited early-onset non-autoimmune hypothyroidism [PDF]

European Journal of Endocrinology, 2007
Objective : Mutations in NKX2.1 , NKX2.5 , FOXE1 and PAX8 genes, encoding for transcription factors involved in the development of the thyroid gland ...
Eva, Al Taji, Heike, Biebermann, Zdenka, Límanová, Olga, Hníková, Jaroslav, Zikmund, Christof, Dame, Annette, Grüters, Jan, Lebl, Heiko, Krude   +8 more
openaire   +2 more sources

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, Volume 48, Issue 8, Page 2180-2189, August 2026.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Expression Landscape and Circadian Regulation of lncRNAs in the Kidney

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger, Fanny Durussel, Muriel Auberson, Dmitri Firsov, Yohan Bignon   +4 more
wiley   +1 more source

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, Volume 117, Issue 8, Page 2029-2039, August 2026.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

Clinicopathological and molecular characterization of HPV‐associated cervical poorly cohesive carcinoma: a rare aggressive entity

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Primary signet‐ring cell carcinoma and poorly differentiated adenocarcinoma with poorly cohesive morphology in the cervix are rare conditions, and their clinicopathological features remain poorly described. This study defines primary cervical poorly differentiated adenocarcinomas meeting the diagnostic criteria for poorly cohesive carcinoma as
Wei Liu, Xiao‐jiang Wang, Yan‐mei Cui, Jing‐cheng Liu, Jiajie Zhang, Li‐bin Zhang, Xi Lei, Xiuqin Weng, Wucheng Shen, Wen‐xiu Miao, Jun‐cheng Ye, Tong‐mei He, Qin Xu, Yi Shi, Dan Hu   +14 more
wiley   +1 more source

Non‐Small Cell Lung Carcinoma Presenting as Isolated Malignant Ascites in the Absence of a Detectable Primary Tumor: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT An 89‐year‐old woman presented with abdominal distension and altered mental status. Non‐portal‐hypertensive ascites suggested spontaneous bacterial peritonitis, but ascitic‐fluid cytology with immunoprofiling and circulating tumor‐DNA confirmed non‐small cell lung carcinoma despite no detectable primary tumor, underscoring early consideration ...
Angad Tiwari, Ashish Sharma, Monica Lewkowicz, Hareesha Rishab Bharadwaj, Khabab Abbasher Hussien Mohamed Ahmed, Edgar Naut   +5 more
wiley   +1 more source

Unexpected Cervical Lymph Node Metastasis Revealing TFE3‐Rearranged Renal Cell Carcinoma: Intraoperative Cytologic Clues to an Occult Renal Primary

Diagnostic Cytopathology, Volume 54, Issue 7, Page 538-541, July 2026.
ABSTRACT TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare subtype of renal carcinoma that may present diagnostic challenges in cytologic specimens, particularly when metastatic disease represents the initial clinical manifestation. We report the case of a 72‐year‐old man presenting with bulky cervical lymphadenopathy clinically suspicious for
Marc P. Pusztaszeri
wiley   +1 more source

Transcriptome of neonatal preBötzinger complex neurones in Dbx1 reporter mice

Scientific Reports, 2017
We sequenced the transcriptome of brainstem interneurons in the specialized respiratory rhythmogenic site dubbed preBötzinger Complex (preBötC) from newborn mice. To distinguish molecular characteristics of the core oscillator we compared preBötC neurons
John A. Hayes, Andrew Kottick, Maria Cristina D. Picardo, Andrew D. Halleran, Ronald D. Smith, Gregory D. Smith, Margaret S. Saha, Christopher A. Del Negro   +7 more
doaj   +1 more source

Update of the risk assessment on emerging and novel brominated flame retardants in food

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The European Commission asked EFSA to update its 2012 risk assessment on Emerging and Novel brominated flame retardants (BFRs) in food. Since the previous Opinion, further information was collected for a total of 27 BFRs. The CONTAM Panel concluded that TDBPP, DBPNG and TBNPA are considered genotoxic and carcinogenic.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Isabelle P. Oswald, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Emilio Benfenati, Diane Benford, Andy Hart, Martin Rose, Henri Schroeder, Christiane Vleminckx, Martine Vrijheid, Edoardo Carnesecchi, Violetta Costanzo, Andrea Gissi, Eirini Kouloura, Luisa Ramos Bordajandi, Francesca Riolo, Christer Hogstrand   +33 more
wiley   +1 more source

Roles of long non‐coding RNAs in gestational diabetes mellitus: Mechanisms and biomarker potential

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Upregulated lncRNAs in GDM Some key lncRNAs (MALAT1, MEG8, SOX2OT and …) show higher expression in GDM. Downregulated lncRNAs in GDM Some key lncRNAs (HCG27, GASS, Pax AS1 and …) show lower expression in GDM. Mechanistic roles lncRNAs regulate trophoblast proliferation, insulin signalling, neonatal and offspring health and other complications related ...
Reza Kouchaki, Fateme Karimi Dermani, Ishwaree Datta, Sahar Moghbelinejad, Nematollah Gheibi, Farideh Movahed, Fatemeh Samieerad, Saeideh Gholamzadeh Khoei, Hamid Sadeghi   +8 more
wiley   +1 more source