Results 41 to 50 of about 766,818 (299)
Tolerance without clonal expansion: Self-antigen-expressing B cells program self-reactive T cells for future deletion [PDF]
, 2008 B cells have been shown in various animal models to induce immunological tolerance leading to reduced immune responses and protection from autoimmunity.
Anderton, Stephen M. +9 more
core +1 more source
International journal of health sciences, 2022 PD-1 or the programmed cell death protein 1 plays a major role in eliciting the immune checkpoint response of T cells. They are the inhibitory receptors induced in activated T cells. The application of these receptors earns a great interest to investigate, in-depth, their mechanism of action and therapeutic success. The US FDA has successfully approved
Muhammad Faraz Shamshad +6 more
openaire +1 more source
Machine and deep learning driven models for the design of heat exchangers with micro-finned tubes
Energy and AIThe design of micro-finned tube heat exchangers is a complex task due to intricate geometry, heat transfer goals, material selection, and manufacturing challenges. Nowadays, mathematical models provide valuable insights, aid in optimization, and allow us
Emad Efatinasab +3 more
doaj +1 more source
Antibodies, 2022 This study aimed to investigate PD-L1 and PD-1 expression in circulating CD20+ cells in diffuse larger B-cell lymphoma (DLBCL) and to evaluate the predictive and diagnostic performance of PD-L1 versus PD-1 expression in circulating CD20+ cells in DLBCL ...
Manal Mohamed Saber
doaj +1 more source
Cell, 2015 Nivolumab and pembrolizumab are monoclonal antibodies that block the programmed death-1 receptor (PD-1, CD279), resulting in dis-inhibition of tumor-specific immune responses. Both are recently approved for use in the treatment of metastatic melanoma, and nivolumab as well for non-small cell lung cancer.
openaire +2 more sources
A structural study of a C3H3 species coadsorbed with CO on Pd(1 1 1) [PDF]
, 2008 The combination of chemical-state-specific C 1s scanned-energy mode photoelectron diffraction (PhD) and O K-edge near-edge X-ray absorption fine structure (NEXAFS) has been used to determine the local adsorption geometry of the coadsorbed C3H3 and CO ...
Allegretti, F. +5 more
core +1 more source
Immunotherapy protocols in lung cancer
Cancer Research, Statistics, and Treatment, 2018 Immunotherapy has emerged as a valuable treatment option in many advanced malignancies (especially lung cancer). The PD-1 inhibitors (nivolumab and pembrolizumab) and the PD-L1 inhibitors (durvalumab and atezolizumab) have been approved for use in ...
Nandini Menon, Sharada Mailankody
doaj +1 more source
PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads [PDF]
, 2013 An estimated 34 million people are living with HIV worldwide (UNAIDS, 2012), with the number of infected persons rising every year. Increases in HIV prevalence have resulted not only from new infections, but also from increases in the survival of HIV ...
Allen, Todd M. +5 more
core +6 more sources
Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2023 Belawan port and coastal areas were also not spared from the impact of the tidal flood. This study aims to determine the performance of the Delft3D hydrodynamic model in simulating sea level and waves in tidal floods at Belawan port and coastal area ...
Rizki Fadhillah Pratama Putra +3 more
doaj +1 more source
A Review of Mechanical Design Approaches for Balanced Robotic Manipulation
RoboticsRobot manipulators are suitable for many industrial tasks, such as assembly and pick-and-place operations. However, high-acceleration motions result in shaking forces and moments to the base, which can cause vibration of the manipulator and instability ...
Yash J. Vyas +2 more
doaj +1 more source