Results 51 to 60 of about 750,934 (136)

Nivolumab plus ipilimumab in the treatment of advanced melanoma. [PDF]

, 2015
Advanced melanoma has historically been a difficult disease to treat due to few effective systemic treatment options. However, over the past few years, scientific advancements in immune checkpoint inhibition have resulted in several novel approaches that
Daud, Adil I, Tsai, Katy K
core   +1 more source

The Recursive Form of Error Bounds for RFS State and Observation with Pd<1

, 2012
In the target tracking and its engineering applications, recursive state estimation of the target is of fundamental importance. This paper presents a recursive performance bound for dynamic estimation and filtering problem, in the framework of the finite
Meng, Huadong, Tong, Huisi, Wang, Xiqin, Zhang, Hao   +3 more
core   +1 more source

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer [PDF]

, 2018
Programmed death 1 (PD-1) is a co-inhibitory receptor in the CD28/CTL-4 family, and functions as a negative regulator of the immune system. Tumor-infiltrating lymphocytes (TIL) in many epithelial cancers express PD-1, suggesting that antitumor immunity ...
Gao, F., Gillanders, W., Muenst, S., Obermann, E., Oertli, D., Soysal, S.   +5 more
core  

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4. [PDF]

, 2019
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments.
Alexandrov, Ludmil B, Allevato, Michael M, Amornphimoltham, Panomwat, Chen, Qianming, Cohen, Ezra EW, Gilardi, Mara, Goto, Yusuke, Gutkind, J Silvio, He, Yudou, Luis Callejas-Valera, Juan, Lyons, J Guy, Martin, Daniel, Mcdermott, James, Molinolo, Alfredo A, Sharabi, Andrew B, Vitale-Cross, Lynn, Wang, Zhiyong, Wu, Victoria H, Yung, Bryan S   +18 more
core  

PD-1 targets CD28 [PDF]

Nature Immunology, 2017
openaire   +2 more sources

The Application of PD-1 Inhibitors in Immunotherapy for Glioblastoma. [PDF]

FASEB J
Dong MZ, Cui M, Qu LZ, Che HY, Guan HJ.
europepmc   +1 more source

PD-1 genetic fate mapping uncovers immune cell diversity mediating the efficacy of combined PD-1 blockade and chemotherapy. [PDF]

Oncoimmunology
Yamaguchi A, Suzuki H, Takasuga S, Tatematsu M, Fuchimukai A, Endo T, Kaya H, Morishita A, Seki S, Imai K, Ebihara T.   +10 more
europepmc   +1 more source

Anti PD-1 protitelesa

Onkologija, 2017
Protein programirane celične smrti 1:PD-1 (Programmed cell death protein 1) je transmembranski protein, ki je izražen na celicah T, B, NK ter monocitih in dendritičnih celicah. Vezava med PD-1 in njegovimi ligandi zavira tumorsko celično apoptozo, spodbuja izčrpanost T-celic in preprečuje aktiven antitumorski odziv, kar posledično omogoča nemoteno rast
openaire   +1 more source

Cortisol Regulates PD-1 and IL-12 in Canine Leishmaniasis. [PDF]

Parasite Immunol
Ito LTS, Umino GM, Guimarães MA, de Souza BMM, Soares SF, Pereira LEAL, de Lima VMF.   +6 more
europepmc   +1 more source

Anti-PD-1 associated retroperitoneal fibrosis

Rheumatology, 2021
Dimitrios Daoussis, Pantelis Kraniotis, Foteini Kalofonou, Haralabos Kalofonos   +3 more
openaire   +2 more sources