Celastrol Inhibits Porcine Epidemic Diarrhea Virus Replication by Promoting ROS-Mediated Apoptosis. [PDF]
Zhu J +8 more
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Establishment of Multiplex Digital PCR Assay for Detection of Four Porcine Enteric Coronaviruses. [PDF]
Han X +9 more
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The non-vesicular cholesterol transporter GRAMD1C is a pan-coronavirus antiviral target. [PDF]
Su Z +11 more
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The nonstructural protein 13 of porcine deltacoronavirus coordinates ATP-driven duplex unwinding and ATP-independent strand annealing for nucleic acid remodeling. [PDF]
Tao L, Zhou Q, Wu C, Jiang H, Huang J.
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Study of the inhibitory effect of STAT1 on PDCoV infection
Veterinary Microbiology, 2022Porcine deltacoronavirus (PDCoV) is an enteropathogen found in many pig producing countries. It can cause acute diarrhea, vomiting, dehydration, and death in newborn piglets, seriously affecting the development of pig breeding industries. To date, our knowledge of the pathogenesis of PDCoV and its interactions with host cell factors remains incomplete.
Jingfei Hu, Yiping Wen, Rui Wu
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Rhodanine derivative LJ001 inhibits TGEV and PDCoV replication in vitro
Transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) are members of the family coronaviridae and mainly cause acute diarrhea/vomiting, dehydration and mortality in piglets, which lead to huge economic losses to the swine industry.
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Porcine deltacoronavirus (PDCoV) infection suppresses RIG-I-mediated interferon-β production
Porcine deltacoronavirus (PDCoV), an emerging animal coronavirus causing enteric disease in pigs, belongs to the newly identified Deltacoronavirus genus in the Coronaviridae family. Although extensive studies have been carried out to investigate the regulation of interferon (IFN) responses by alphacoronaviruses, betacoronaviruses, and ...
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PGAM5 degrades PDCoV N protein and activates type I interferon to antagonize viral replication
Journal of Virology, 2023ABSTRACT In recent years, porcine deltacoronavirus (PDCoV) has become a new intestinal coronavirus in pigs, rapidly spreading across multiple countries and causing significant financial losses in the global pig industry. Currently, no effective commercial vaccine is available to prevent this virus’ spread.
wen zhang, Guang-zhi Tong, Tongling Shan
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Porcine deltacoronavirus (PDCoV) is the etiological agent of acute diarrhoea and vomiting in pigs, threatening the swine industry worldwide. Although several PDCoV studies have been conducted in China, more sequence information is needed to understand the molecular characterization of PDCoV.
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