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Targeting host integrated stress response: lead discovery of flavonoid compounds active against coronaviruses PEDV and PDCoV

RSC Medicinal Chemistry
We have discovered a new class of flavonoid-based host integrated stress response (ISR) activators that exhibit potent antiviral activity against coronaviruses PEDV and PDCoV. They are host-directed antivirals (HDAs).
Liang Yi   +6 more
openaire   +2 more sources

Effective preparation and immunogenicity analysis of antigenic proteins for prevention of porcine enteropathogenic coronaviruses PEDV/TGEV/PDCoV

International Journal of Biological Macromolecules
Porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) cause highly contagious gastrointestinal damage to piglets with high coinfection in clinical. However, there is no available trivalent vaccine against the three viruses.
Xinhao, Jia   +9 more
openaire   +2 more sources

Resveratrol Inhibits Pdcov Infection by Activating Sirt1 to Promote Interferon Production

Songqi Wang   +10 more
openaire   +1 more source

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