Results 41 to 50 of about 4,222 (186)

table9_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.xlsx

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source

Insights into prognosis and immune infiltration of cuproptosis-related genes in breast cancer

Frontiers in Immunology, 2022
IntroductionBreast cancer (BC) has been ranking first in incidence and the leading cause of death among female cancers worldwide based on the latest report. Regulated cell death (RCD) plays a significant role in tumor initiation and provides an important
Tingting Huang, Yankuo Liu, Jiwei Li, Bingbing Shi, Zhengda Shan, Zhiyuan Shi, Zhangru Yang   +6 more
doaj   +1 more source

Identification of cuproptosis-related genes for predicting the development of prostate cancer

Open Medicine, 2023
Copper can be toxic at very high intracellular concentrations and can inhibit prostate cancer (PCa) progression. Recently, a study reported the mechanism of cuproptosis and the potentially associated genes.
Wang Xin’an, Chen Xi, Xu Chengdang, Zhou Weidong, Wu Denglong   +4 more
doaj   +1 more source

table8_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.xlsx

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source

Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth

Cancer & Metabolism, 2021
Background Pyruvate dehydrogenase complex (PDC) plays a central role in carbohydrate metabolism, linking cytoplasmic glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle.
Nancy P. Echeverri Ruiz, Vijay Mohan, Jinghai Wu, Sabina Scott, McKenzie Kreamer, Martin Benej, Tereza Golias, Ioanna Papandreou, Nicholas C. Denko   +8 more
doaj   +1 more source

Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis

Journal for ImmunoTherapy of Cancer, 2023
Background anti-Programmed Death-1 (anti-PD-1) immunotherapy has shown promising manifestation in improving the survival rate of patients with advanced melanoma, with its efficacy closely linked to Programmed cell death-Ligand 1 (PD-L1) expression ...
Jie Wu, Xiang Chen, Qian Tao, Nian Liu, Mingjie Yan, Cong Peng   +5 more
doaj   +1 more source

image5_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.tif

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source

table4_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.xlsx

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source

table3_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.xlsx

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source

table1_Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer.xlsx

, 2022
Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells.
Xiaoji Peng (13210572), Liying Song (2802685), Anqi Jiang (4583380), Langmei Deng (11845673), Hanqing Zeng (694794)   +4 more
core   +1 more source