Results 21 to 30 of about 359,289 (223)

Elucidation of the Translation Initiation Factor Interaction Network of Haloferax volcanii Reveals Coupling of Transcription and Translation in Haloarchaea

Frontiers in Microbiology, 2021
Translation is an important step in gene expression. Initiation of translation is rate-limiting, and it is phylogenetically more diverse than elongation or termination. Bacteria contain only three initiation factors. In stark contrast, eukaryotes contain
Franziska Schramm, Andreas Borst, Uwe Linne, Jörg Soppa   +3 more
doaj   +1 more source

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]

, 2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom, Bao, Katherine, Birnberg, Andrew, Chou, Seemay, Krogan, Nevan J, Schulze-Gahmen, Ursula, Upton, Heather, Zhou, Qiang   +7 more
core   +1 more source

A stochastic model for simulating ribosome kinetics in vivo.

PLoS Computational Biology, 2020
Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and ...
Eric Charles Dykeman
doaj   +1 more source

The Peptide PbrPSK2 From Phytosulfokine Family Induces Reactive Oxygen Species (ROS) Production to Regulate Pear Pollen Tube Growth

Frontiers in Plant Science, 2020
Phytosulfokines (PSKs) are plant peptide growth factors that participate in multiple biological processes, including cell elongation and immune signaling. However, little is known about PSKs in Rosaceae species.
Xiaobing Kou, Qian Liu, Yangyang Sun, Peng Wang, Shaoling Zhang, Juyou Wu   +5 more
doaj   +1 more source

Epigallocatechine-3-gallate Inhibits the Adipogenesis of Human Mesenchymal Stem Cells via the Regulation of Protein Phosphatase-2A and Myosin Phosphatase

Cells, 2022
Epigallocatechin-3-gallate (EGCG) has widespread effects on adipocyte development. However, the molecular mechanisms of EGCG are not fully understood. We investigate the adipogenic differentiation of human-derived mesenchymal stem cells, including lipid ...
Bálint Bécsi, Zoltán Kónya, Anita Boratkó, Katalin Kovács, Ferenc Erdődi   +4 more
doaj   +1 more source

Regulation of the activity of eukaryotic peptide elongation factor 1 by autocatalytic phosphorylation [PDF]

European Journal of Biochemistry, 1985
Highly purified peptide elongation factor 1 from rabbit reticulocytes liberates the terminal phosphate from [γ‐32P]GTP and incorporates it into its own protein. Approximately one phosphate residue becomes bound by one molecule of the factor. Only the eEF‐1α subunit of the factor (Mr 53000) becomes phosphorylated as revealed by polyacrylamide gel ...
Z, Tuhácková, J, Ullrichová, J, Hradec   +2 more
openaire   +2 more sources

Bacterial Extracellular DNA Promotes β-Amyloid Aggregation

Microorganisms, 2021
Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj   +1 more source

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex [PDF]

, 2018
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause.
Alonso-Nunez, Bahler, Bahler, Banks, Buchan, Cairns, Charles AS Banks, Chou, Christopher W Seidel, Coudreuse, Dana M Gibbon, Elmendorf, Florens, Garg, He, He, Joan W Conaway, Kim, Kimura, Kimura, Kitts, Kong, Langmead, Laurence A Florens, Li, Lin, Luo, Luo, Michael P Washburn, Miller, Monahan, Nimisha Sharma, Oliva, Preeti Dabas, Quinlan, Robinson, Ronald C Conaway, Rustici, Shilatifard, Shilatifard, Simone, Simone, Sneha Gopalan, Sobhian, Suarez, Szklarczyk, Tabb, Takahashi, Thorvaldsdottir, Tsai, Ward, Washburn, Ying Zhang, Yokoyama, Zhang   +54 more
core   +1 more source

CTP can replace GTP in reactions catalyzed by eukaryotic peptide elongation factor 1 [PDF]

FEBS Letters, 1984
In several reactions catalyzed by highly purified peptide elongation factor 1 from rabbit reticulocytes, GTP may be fully replaced by CTP but not by ATP or UTP. This holds true for the factor‐dependent binding of aminoacyl‐tRNA to ribosomes, GTPase activity, GTP‐dependent autophosphorylation of the factor protein and binding of cholesteryl 14 ...
Tuháčková, Z., Havránek, M., Hradec, J.   +2 more
openaire   +2 more sources

Investigation of Parameters that Affect Resin Swelling in Green Solvents

ChemistryOpen, 2020
The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated.
Chidi Amadi‐Kamalu, Holly Clarke, Matthew McRobie, James Mortimer, Prof. Michael North, Yanrui Ran, Dr. Anne Routledge, Dani Sibbald, Matthew Tickias, Kai Tse, Helen Willway   +10 more
doaj   +1 more source