Results 31 to 40 of about 53,655 (285)

Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa, Gopalan, Began, Hauser, Charlotte A. E., Joshi, Mangesh, Lakshmanan, Anupama, Lam, Dang Hoang, Mishra, Archana, Reithofer, Michael R., Wang, Shu   +8 more
core   +1 more source

Immunomodulatory PEG-CRGD Hydrogels Promote Chondrogenic Differentiation of PBMSCs

Pharmaceutics, 2022
Cartilage damage is a common injury. Currently, tissue engineering scaffolds with composite seed cells have emerged as a promising approach for cartilage repair.
Meng Yang, Rong-Hui Deng, Fu-Zhen Yuan, Ji-Ying Zhang, Zi-Ning Zhang, You-Rong Chen, Jia-Kuo Yu   +6 more
doaj   +1 more source

Smart systems related to polypeptide sequences [PDF]

, 2016
Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence.
Franco García, María Lourdes, Puiggalí Bellalta, Jordi, Valle Mendoza, Luis Javier del   +2 more
core   +2 more sources

Hydrogelation tunability of bioinspired short peptides

Soft Matter, 2022
The fragment 269–273 of nucleophosmin 1 protein, was investigated in its ability to form hydrogels in four different forms deriving from the partial, absent and complete amidation/acetylation at the extremities of the backbone.
Sara La Manna, Daniele Florio, Valeria Panzetta, Valentina Roviello, Paolo Antonio Netti, Concetta Di Natale, Daniela Marasco   +6 more
openaire   +3 more sources

Bioinspired mineralization of calcium carbonate in peptide hydrogel acting as a multifunctional three-dimensional template

Journal of Asian Ceramic Societies, 2021
Biomineralization is the process by which biominerals, minerals composed of bioinorganic matter possessing a controlled structure and orientation and a biomacromolecular assembly with an ordered structure that acts as a 3D template, are formed.
Kazuki Murai, Yosuke Funamizu, Toshihiko Ogura, Keishi Nishio   +3 more
doaj   +1 more source

The Effects of a Short Self-Assembling Peptide on the Physical and Biological Properties of Biopolymer Hydrogels

Pharmaceutics, 2021
Hydrogel scaffolds have attracted much interest in the last few years for applications in the field of bone and cartilage tissue engineering. These scaffolds serve as a convenient three-dimensional structure on which cells can grow while sensing the ...
Sumit Chowdhuri, Moumita Ghosh, Lihi Adler-Abramovich, Debapratim Das   +3 more
doaj   +1 more source

Peptide-Modified Chitosan Hydrogels Accelerate Skin Wound Healing by Promoting Fibroblast Proliferation, Migration, and Secretion

Cell Transplantation, 2017
Skin wound healing is a complicated process that involves a variety of cells and cytokines. Fibroblasts play an important role in this process and participate in transformation into myofibroblasts, the synthesis of extracellular matrix (ECM) and fibers ...
Xionglin Chen, Min Zhang, Shixuan Chen, Xueer Wang, Zhihui Tian, Yinghua Chen, Pengcheng Xu, Lei Zhang, Lu Zhang, Lin Zhang   +9 more
doaj   +1 more source

Immune Enhancement by the Tetra-Peptide Hydrogel as a Promising Adjuvant for an H7N9 Vaccine against Highly Pathogenic H7N9 Virus

Vaccines, 2022
Background: Short peptide hydrogel was reported as a possible adjuvant for vaccines. In order to evaluate whether the Tetra-Peptide Hydrogel can be a promising adjuvant for an H7N9 vaccine against the highly pathogenic H7N9 virus, we conducted this study.
Xiaoxin Wu, Songjia Tang, Zhehua Wang, Xiaoyun Ma, Lingjian Zhang, Fen Zhang, Lanlan Xiao, Shuai Zhao, Qian Li, Ying Wang, Qingjing Wang, Keda Chen   +11 more
doaj   +1 more source

QHREDGS enhances tube formation, metabolism and survival of endothelial cells in collagen-chitosan hydrogels. [PDF]

PLoS ONE, 2013
Cell survival in complex, vascularized tissues, has been implicated as a major bottleneck in advancement of therapies based on cardiac tissue engineering.
Jason W Miklas, Susan M Dallabrida, Lewis A Reis, Nesreen Ismail, Maria Rupnick, Milica Radisic   +5 more
doaj   +1 more source

Self-assembly of Fmoc-tetrapeptides based on the RGDS cell adhesion motif [PDF]

, 2011
Self-assembly in aqueous solution has been investigated for two Fmoc [Fmoc ¼ N-(fluorenyl)-9-methoxycarbonyl] tetrapeptides comprising the RGDS cell adhesion motif from fibronectin or the scrambled sequence GRDS.
Alemán, Carlos, Castelletto, Valeria, Cheng, Ge, Hamley, Ian W., Hicks, Matthew R., López-Pérez, Daniel E., Moulton, Claire M., Revilla-López-Pérez, Guillermo, Rodger, Alison   +8 more
core   +1 more source