Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening [PDF]
eLifePhage-derived peptidoglycan hydrolases (i.e. lysins) are considered promising alternatives to conventional antibiotics due to their direct peptidoglycan degradation activity and low risk of resistance development.
Li Zhang +11 more
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Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics [PDF]
mBio, 2020 The Escherichia coli microcin C (McC) and related compounds are potent Trojan horse peptide-nucleotide antibiotics. The peptide part facilitates transport into sensitive cells.
Eldar Yagmurov +7 more
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Effect of nitrogen on activity of peptide hydrolases and protein content in caryopses and flag leaf of barley in ontogenesis [PDF]
E3S Web of Conferences, 2020 The aim of the research was to study the influence peculiarities of different levels of nitrogen nutrition on the activity of peptide hydrolases and protein content in ontogeny of barley plants.The paper discusses the content of total nitrogen, protein ...
Gamzaeva R S
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Comparisons of Peptide Hydrolase Activities in Cereals [PDF]
Plant Physiology, 1984 Carboxypeptidase activity (hydrolysis of N-carbobenzoxy-l-phenylalanyl-l-alanine) is high in a number of temperate zone cereals, originating in Asia Minor (wheat, barley, oats, wild oats, rye, triticale) compared to other cereals originating in central America or Asia (maize, sorghum, rice).
Michael J. Winspear +3 more
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Short Peptides for Hydrolase Supramolecular Mimicry and Their Potential Applications [PDF]
Gels, 2023 Hydrolases are enzymes that have found numerous applications in various industrial sectors spanning from pharmaceuticals to foodstuff and beverages, consumers’ products such as detergents and personal care, textiles, and even for biodiesel production and environmental bioremediation.
Paola Alletto +2 more
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Specificity determinants of acylaminoacyl‐peptide hydrolase [PDF]
Protein Science, 1992 AbstractIn an attempt to explore how specific features of the substrate's primary structure may affect the activity of rabbit muscle acylaminoacyl‐peptide hydrolase (EC 3.4.19.1), a number of acetylated peptides containing specific amino acid replacements in specific positions were prepared and compared as substrates for the hydrolase.
Radha Krishna, Finn Wold
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INHIBITION AND ACTIVATION OF BARLEY PEPTIDE HYDROLASES I. PEPTIDE HYDROLASE A [PDF]
Journal of the Institute of Brewing, 1971 Barley peptide hydrolase A acting on N-benzoyl-dl-arginine-p-nitroanilide as substrate is inhibited by the sulphydryl reagents N-ethyl maleimide and p-chloro-mercuriphenyl sulphonate. Oxidized glutathione, however, is non-inhibitory and several sulphydryl compounds are not stimulatory.
W. C. Burger +2 more
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Peptide hydrolases in the brush border and soluble fractions of small intestinal mucosa of rat and man [PDF]
, 1972 Y. S. Kim, W. Birtwhistle, Y. W. Kim
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Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide [PDF]
Molecular Neurodegeneration, 2009 Abstract Background The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain including monomers, oligomers, and aggregates, and in senile plaques, fibrils.
Rina Yamin +4 more
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Isolation and Characterisation of Peptide Hydrolases from the Maize Root [PDF]
European Journal of Biochemistry, 1979 The maize root has two main proteinase and carboxypeptidase components. Proteinase I and carboxypeptidase I, which predominate in older plants, appear to have a serine group at their active sites and have been estimated to have molecular weights of approximately 54000 and 77000 respectively.
J D, Shannon, W, Wallace
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