Results 11 to 20 of about 254,967 (163)

Phage-displayed peptide libraries [PDF]

open access: yesCurrent Opinion in Biotechnology, 1998
Over the past year, significant advances have been achieved through the use of phage-displayed peptide libraries. A wide variety of bioactive molecules, including antibodies, receptors and enzymes, have selected high-affinity and/or highly-specific peptide ligands from a number of different types of peptide library.
M B, Zwick, J, Shen, J K, Scott
openaire   +2 more sources

Large‐scale survey and database of high affinity ligands for peptide recognition modules

open access: yesMolecular Systems Biology, 2020
Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners.
Joan Teyra   +13 more
doaj   +1 more source

Acrylamide neurotoxicity on the cerebrum of weaning rats

open access: yesNeural Regeneration Research, 2015
The mechanism underlying acrylamide-induced neurotoxicity remains controversial. Previous studies have focused on acrylamide-induced toxicity in adult rodents, but neurotoxicity in weaning rats has not been investigated.
Su-min Tian   +5 more
doaj   +1 more source

Pharmacophore Generation from a Drug-like Core Molecule Surrounded by a Library Peptide via the 10BASEd-T on Bacteriophage T7

open access: yesMolecules, 2014
We have achieved site-specific conjugation of several haloacetamide derivatives into designated cysteines on bacteriophage T7-displayed peptides, which are fused to T7 capsid protein gp10.
Yuuki Tokunaga   +5 more
doaj   +1 more source

Screening technology of cyclic peptide library based on gene encoding

open access: yesMedicine in Drug Discovery, 2022
As a powerful tool for the discovery of peptide compounds, high-throughput library screening technology can also perform multitarget screening with high chemical diversity as a condition, which accelerates the process of exploring high-affinity peptide ...
Yangqiang Chen   +5 more
doaj   +1 more source

In vivo tracking of human adipose-derived stem cells labeled with ferumoxytol in rats with middle cerebral artery occlusion by magnetic resonance imaging

open access: yesNeural Regeneration Research, 2015
Ferumoxytol, an iron replacement product, is a new type of superparamagnetic iron oxide approved by the US Food and Drug Administration. Herein, we assessed the feasibility of tracking transplanted human adipose-derived stem cells labeled with ...
Yan Yin   +5 more
doaj   +1 more source

12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation

open access: yesNeural Regeneration Research, 2015
Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini   +4 more
doaj   +1 more source

Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014

open access: yesNeural Regeneration Research, 2015
Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research.
Guang-yao Liu   +3 more
doaj   +1 more source

Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury

open access: yesNeural Regeneration Research, 2015
Hydrogen can relieve tissue-damaging oxidative stress, inflammation and apoptosis. Injection of hydrogen-rich saline is an effective method for transporting molecular hydrogen.
Jian-long Wang   +6 more
doaj   +1 more source

Nerve autografts and tissue-engineered materials for the repair of peripheral nerve injuries: a 5-year bibliometric analysis

open access: yesNeural Regeneration Research, 2015
With advances in biomedical methods, tissue-engineered materials have developed rapidly as an alternative to nerve autografts for the repair of peripheral nerve injuries. However, the materials selected for use in the repair of peripheral nerve injuries,
Yuan Gao   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy