Results 241 to 250 of about 379,196 (358)
Investigation of the `switch-epitope' concept with random peptide libraries displayed as thioredoxin loop fusions [PDF]
Brian C. Tripp+4 more
openalex +1 more source
Polyglutamine (polyQ) tract expansion (≥ 36 amino acids) within the N‐terminal region of the Huntingtin protein (Httex1) causes Huntington's disease (HD), for which the underlying causes are not well‐understood. The authors performed computer simulations to understand the cause of HD at the molecular level.
Priyesh Mohanty+2 more
wiley +1 more source
Identification of a potent PCNA-p15-interaction inhibitor by autodisplay-based peptide library screening. [PDF]
Hardebeck S+4 more
europepmc +1 more source
Automating Parallel Peptide Synthesis for the Production of PNA Library Arrays [PDF]
Stefan Matysiak+2 more
openalex +1 more source
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang+6 more
wiley +1 more source
Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands [PDF]
Yingdong Zhao+9 more
openalex +1 more source
DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy
This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang+13 more
wiley +1 more source
Discovery and characterization of anti-cancer peptides from a random peptide library. [PDF]
Puvvula PK, Moon AM.
europepmc +1 more source