Results 21 to 30 of about 254,967 (163)
Hydrogen sulfide intervention in focal cerebral ischemia/reperfusion injury in rats
Neural Regeneration Research, 2015 The present study aimed to explore the mechanism underlying the protective effects of hydrogen sulfide against neuronal damage caused by cerebral ischemia/reperfusion.
Xin-juan Li +6 more
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Frontiers in Medicine, 2020 Middle ear ailments include a broad range of pathological conditions. Otitis media is the leading middle ear disease of childhood, which incurs significant health care resources in developed countries and, in developing countries, causes significant ...
Arwa Kurabi +7 more
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Erythromycin Resistance Peptides Selected from Random Peptide Libraries [PDF]
Journal of Biological Chemistry, 1997 Translation of a 5-codon mini-gene encoded in Escherichia coli 23 S rRNA was previously shown to render cells resistant to erythromycin (Tenson, T., DeBlasio, A., and Mankin, A. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5641-5646). Erythromycin resistance was mediated by a specific interaction of the 23 S rRNA-encoded pentapeptide with the ribosome.
T, Tenson +3 more
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Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library
BMC Biotechnology, 2007 Background Amino acid sequence diversity is introduced into a phage-displayed peptide library by randomizing library oligonucleotide DNA. We recently evaluated the diversity of peptide libraries displayed on T7 lytic phage and M13 filamentous phage and ...
McMahon James B +4 more
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Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies
Frontiers in Chemistry, 2020 Backbone macrocyclic structures are often found in diverse bioactive peptides and contribute to greater conformational rigidity, peptidase resistance, and potential membrane permeability compared to their linear counterparts.
Koki Shinbara +4 more
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Sweetening Cyclic Peptide Libraries [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
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Combinatorial Peptide Libraries: Mining for Cell-Binding Peptides [PDF]
Chemical Reviews, 2013 The surface of a cell represents a collection of macromolecules, which provides the cell with a unique cellular landscape specific to the type and state of the cell. Ligands that discriminate between subtle differences in cell surface phenotypes have utility in a wide variety of research and clinical applications.
Bethany Powell, Gray, Kathlynn C, Brown
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Neural Regeneration Research, 2015 The Wnt/β-catenin signaling pathway plays a crucial role in neural development, axonal guidance, neuropathic pain remission and neuronal survival. In this study, we initially examined the effect of rapamycin on the Wnt/β-catenin signaling pathway after ...
Kai Gao +7 more
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Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop
Neural Regeneration Research, 2015 Curcumin has been shown to significantly improve spatial memory impairment induced by HIV-1 gp120 V3 in rats, but the electrophysiological mechanism remains unknown.
Ling-ling Shen +11 more
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Molecules, 2014 The design, synthesis and screening of diversity-oriented peptide libraries using a “libraries from libraries” strategy for the development of inhibitors of α1-antitrypsin deficiency are described. The major buttress of the biochemical approach presented
Yi-Pin Chang, Yen-Ho Chu
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