Results 181 to 190 of about 24,252 (260)
The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley +1 more source
Peptide YY and ghrelin predict craving and risk for relapse in abstinent smokers. [PDF]
al'Absi M, Lemieux A, Nakajima M.
europepmc +1 more source
Evaluating Large‐Language Models in Bioinformatics Applications
This work systematically evaluates advanced large language models across six representative bioinformatics tasks, from drug–drug interaction prediction and molecular optimization to single‐cell annotation and computational biology problem solving. The benchmark quantifies both their promise and limitations, offering practical guidance for prompt design,
Hengchuang Yin +9 more
wiley +1 more source
SGLT‐2 Inhibitors are Associated With a Lower Risk of Multiple Myeloma
ABSTRACT Aims We aimed to investigate drug response of sodium‐glucose transport protein‐2 inhibitors (SGLT2i) in multiple myeloma (MM), as SGLT2i have potential favorable effects on conditions related to MM. Methods We conducted a pharmacoepidemiologic study with a US nationwide health insurance claim data using Cox models to investigate the ...
Enze Liu +6 more
wiley +1 more source
ABSTRACT Background As poor sleep negatively impacts on adiposity, there is interest in examining whether improving sleep can improve adiposity markers. We reviewed studies aimed at improving sleep using (1) cognitive behavioral therapy for insomnia (CBT‐I) and/or sleep hygiene and (2) sleep extension on adiposity markers, dietary intake, and physical ...
Samiul A. Mostafa +7 more
wiley +1 more source
Low Weight Loss Response to Incretin Analogs: A Systematic Review
ABSTRACT The development of GLP‐1 and GIP analogs has been a significant breakthrough in type 2 diabetes and obesity pharmacotherapy. However, individual responses to these medications can vary widely. This systematic review examines factors associated with low or no weight loss response to GLP‐1 and GIP analogs. Key predictors of poor response include
Pamela S. Gaskin, Peter S. Chami
wiley +1 more source
GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani +8 more
wiley +1 more source
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong +6 more
wiley +1 more source

