Results 201 to 210 of about 24,252 (260)
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Current Opinion in Endocrinology, Diabetes & Obesity, 2008
This review discusses recent studies examining the effects of peptide YY on energy homeostasis, highlights the emerging hedonic effects of peptide YY and evaluates the therapeutic potential of the peptide YY system.A role for exogenous PYY3-36 as an anorectic agent in obese humans and rodents has been established and weight loss effects demonstrated in
Keval, Chandarana, Rachel, Batterham
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This review discusses recent studies examining the effects of peptide YY on energy homeostasis, highlights the emerging hedonic effects of peptide YY and evaluates the therapeutic potential of the peptide YY system.A role for exogenous PYY3-36 as an anorectic agent in obese humans and rodents has been established and weight loss effects demonstrated in
Keval, Chandarana, Rachel, Batterham
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A Nonamidated Peptide Homologous to Porcine Peptide YY and Neuropeptide YY*
Endocrinology, 1985A 37-residue peptide has been purified from the endocrine pancreas of the anglerfish. The first 36 residues were sequenced by gas phase Edman degradation. The sequence at the carboxyl-terminus was determined by sequencing the carboxyl-terminal tryptic dipeptide.
P C, Andrews +3 more
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Peptide YY and appetite control
Current Opinion in Pharmacology, 2004Peptide YY (PYY) is an important gut hormone synthesized and secreted by the gastrointestinal tract. Peripheral administration of PYY(3-36), one of the circulating forms of PYY, is known to inhibit food intake. This anorexigenic effect is masked by stress inhibition of appetite, and it is therefore important for animals to be thoroughly acclimatised ...
B M C, McGowan, S R, Bloom
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Peptide YY in gastrointestinal disorders
Peptides, 2002The changes in PYY in several gastrointestinal disorders and their possible clinical implications are reviewed. The changes in PYY seem to be an adaptive response to alterations in the patho-physiological condition caused by the disease. This becomes evident in gastrointestinal disorders such as diabetes gastroenteropathy, inflammatory bowel diseases ...
Magdy, El-Salhy +2 more
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Physiology & Behavior, 2009
Obtaining a fuller understanding of gut hormones as mediators of appetite regulation and energy homeostasis has never been so important with obesity rates increasing at pandemic proportions. The role of the gut hormone peptide YY 3-36 (PYY3-36) in particular has sparked interest since the discovery of its anorectic effect in obese rodents and humans ...
Marianne T, Neary, Rachel L, Batterham
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Obtaining a fuller understanding of gut hormones as mediators of appetite regulation and energy homeostasis has never been so important with obesity rates increasing at pandemic proportions. The role of the gut hormone peptide YY 3-36 (PYY3-36) in particular has sparked interest since the discovery of its anorectic effect in obese rodents and humans ...
Marianne T, Neary, Rachel L, Batterham
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Peptide YY receptors in the brain
Biochemical and Biophysical Research Communications, 1988Radiolabelled ligand binding studies demonstrated that specific receptors for peptide YY are present in the porcine as well as the canine brains. Peptide YY was bound to brain tissue membranes via high-affinity (dissociation constant, 1.39 X 10(-10)M) and low-affinity (dissociation constant, 3.72 X 10(-8)M) components.
A, Inui +9 more
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Coffee, Hunger, and Peptide YY
Journal of the American College of Nutrition, 2012There is evidence from several empirical studies suggesting that coffee may help people control body weight. Our objective was to assess the effects of caffeine, caffeinated coffee, and decaffeinated coffee, both alone and in combination with 75 g of glucose, on perceived hunger and satiety and related peptides.We conducted a placebo-controlled single ...
James A, Greenberg, Allan, Geliebter
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Current Opinion in Endocrinology and Diabetes, 2006
Caroline R Abbott, Stephen R Bloom
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Caroline R Abbott, Stephen R Bloom
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[Pro34]peptide YY is a Y1-selective agonist at peptide YY/neuropeptide Y receptors
European Journal of Pharmacology: Molecular Pharmacology, 1994We have investigated binding and functional effects of a new peptide YY analogue, [Pro34]peptide YY, at Y1 and Y2-like subtypes of receptors for peptide YY and neuropeptide Y. In binding studies [Pro34]peptide YY had a similarly high affinity as peptide YY to human Y1-like receptors in SK-N-MC cells, a human neuroblastoma cell line of presumed ...
Grandt, D. +9 more
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Neural regulation of peptide YY secretion
Regulatory Peptides, 1993The purpose of these experiments was to investigate the neural control of peptide YY (PYY) secretion. The effects of various pharmacological manipulations and vagotomy on peptide YY (PYY) secretion was examined in dogs. Atropine, hexamethonium and atropine plus hexamethonium treatment blocked food-induced release of PYY significantly.
T, Zhang +5 more
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