Results 91 to 100 of about 11,450 (169)

Functional profiling of CHAP domain-containing peptidoglycan hydrolases of Staphylococcus aureus USA300 uncovers potential targets for anti-staphylococcal therapies

International Journal of Medical Microbiology
The bacterial pathogen Staphylococcus aureus employs a thick cell wall for protection against physical and chemical insults. This wall requires continuous maintenance to ensure strength and barrier integrity, but also to permit bacterial growth and ...
Min Wang, Xiaofang Li, Francis M. Cavallo, Harita Yedavally, Sjouke Piersma, Elisa J.M. Raineri, Elias Vera Murguia, Jeroen Kuipers, Zhenhua Zhang, Jan Maarten van Dijl, Girbe Buist   +10 more
doaj   +1 more source

Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40—Bacillus Specific Endolysins

Viruses, 2018
Three Bacillus bacteriophage-derived endolysins, designated PlyP56, PlyN74, and PlyTB40, were identified, cloned, purified, and characterized for their antimicrobial properties. Sequence alignment reveals these endolysins have an N-terminal enzymatically
Irina Etobayeva, Sara B. Linden, Farhang Alem, Laith Harb, Lucas Rizkalla, Philip D. Mosier, Allison A. Johnson, Louise Temple, Ramin M. Hakami, Daniel C. Nelson   +9 more
doaj   +1 more source

Peptidoglycan Hydrolases of Local Lactic Acid Bacteria from Kazakh Traditional Food

Central Asian Journal of Global Health, 2014
Introduction: Peptidoglycan (PG) is a major component of the cell wall of Gram-positive bacteria and is essential for maintaining the integrity of the bacterial cell and its shape. The bacteria synthesize PG hydrolases, which are capable of cleaving the covalent bonds of PG.
Serik Shaikhin, Asel Moldagulova, Abzal Kazhybayev, Markhabat Kairova, Constantine Lee, Maira Urazova, Kairtai Almagambetov   +6 more
openaire   +4 more sources

A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis in female mice. [PDF]

Nat Commun, 2023
Gao J, Wang L, Jiang J, Xu Q, Zeng N, Lu B, Yuan P, Sun K, Zhou H, He X.   +9 more
europepmc   +1 more source

Sporulation Activated via σ^W Protects Bacillus from a Tse1 Peptidoglycan Hydrolase Type VI Secretion System Effector. [PDF]

Microbiol Spectr, 2023
Pérez-Lorente AI, Molina-Santiago C, de Vicente A, Romero D.   +3 more
europepmc   +1 more source

Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291. [PDF]

Environ Microbiol, 2021
Zhu D, Patabendige HMLW, Tomlinson BR, Wang S, Hussain S, Flores D, He Y, Shaw LN, Sun X.   +8 more
europepmc   +1 more source

The Phagocytosis of <i>Lacticaseibacillus casei</i> and Its Immunomodulatory Properties on Human Monocyte-Derived Dendritic Cells Depend on the Expression of Lc-p75, a Bacterial Peptidoglycan Hydrolase. [PDF]

Int J Mol Sci, 2022
Tóth M, Muzsai S, Regulski K, Szendi-Szatmári T, Czimmerer Z, Rajnavölgyi É, Chapot-Chartier MP, Bácsi A.   +7 more
europepmc   +1 more source

Chapter 12. Measure of peptidoglycan hydrolase activity Running head: peptidoglycan remodelling enzymes

, 2017
Most of the gene clusters encoding multiprotein complexes of the bacterial cell envelope, such as conjugation and secretion systems, Type IV pili and flagella, bear a gene encoding an enzyme with peptidoglycan hydrolase activity. These enzymes are usually glycoside hydrolases that cleave the glycan chains of the peptidoglycan.
Cascales, E., Santin, Yoann
openaire   +1 more source

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile. [PDF]

mBio, 2021
Garcia-Garcia T, Poncet S, Cuenot E, Douché T, Giai Gianetto Q, Peltier J, Courtin P, Chapot-Chartier MP, Matondo M, Dupuy B, Candela T, Martin-Verstraete I.   +11 more
europepmc   +1 more source

Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease

The Cell Surface
A defining feature of bacteria is the peptidoglycan cell wall which provides structural integrity and prevents osmotic lysis. While peptidoglycan hydrolases are required for daughter cell separation, dysregulated cell wall degradation may result in cell ...
Viktor H. Mebus, Larissa M. Busch, Morten Børre, Tobias K. Nielsen, Martin Saxtorph Bojer, Camilla Henriksen, Maria D. Barbuti, Danae M. Angeles, Kamilla Brejndal, Stephan Michalik, Manuela Gesell Salazar, Morten Kjos, Uwe Völker, Birgitte H. Kallipolitis, Dorte Frees   +14 more
doaj   +1 more source