Results 31 to 40 of about 11,450 (169)

Peptidoglycan Hydrolases of Escherichia coli [PDF]

Microbiology and Molecular Biology Reviews, 2011
SUMMARYThe review summarizes the abundant information on the 35 identified peptidoglycan (PG) hydrolases ofEscherichia coliclassified into 12 distinct families, including mainly glycosidases, peptidases, and amidases. An attempt is also made to critically assess their functions in PG maturation, turnover, elongation, septation, and recycling as well as
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One fold, many functions—M23 family of peptidoglycan hydrolases

Frontiers in Microbiology, 2022
Bacterial cell walls are the guards of cell integrity. They are composed of peptidoglycan that provides rigidity to sustain internal turgor and ensures isolation from the external environment. In addition, they harbor the enzymatic machinery to secure cell wall modulations needed throughout the bacterial lifespan.
Alicja Razew, Jan-Niklas Schwarz, Paweł Mitkowski, Izabela Sabala, Magdalena Kaus-Drobek   +4 more
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Characterisation of the peptidoglycan hydrolases of Listeria monocytogenes EGD [PDF]

FEMS Microbiology Letters, 2006
The peptidoglycan hydrolase profile of Listeria monocytogenes EGD has been characterised under a variety of environmental and physiological conditions, using renaturing sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The profiles show activities ranging from 29 to 186 kDa.
A M, McLaughlan, S J, Foster
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Coordinated and Distinct Roles of Peptidoglycan Carboxypeptidases DacC and DacA in Cell Growth and Shape Maintenance under Stress Conditions

Microbiology Spectrum, 2023
Peptidoglycan (PG) is an essential bacterial architecture pivotal for shape maintenance and adaptation to osmotic stress. Although PG synthesis and modification are tightly regulated under harsh environmental stresses, few related mechanisms have been ...
Umji Choi, Si Hyoung Park, Han Byeol Lee, Ji Eun Son, Chang-Ro Lee   +4 more
doaj   +1 more source

Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin. [PDF]

Microb Biotechnol
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Ansari F, Nagar V.
europepmc   +2 more sources

Potential Role of the Host-Derived Cell-Wall Binding Domain of Endolysin CD16/50L as a Molecular Anchor in Preservation of Uninfected Clostridioides difficile for New Rounds of Phage Infection

Microbiology Spectrum, 2022
Endolysin is a phage-encoded cell-wall hydrolase which degrades the peptidoglycan layer of the bacterial cell wall. The enzyme is often expressed at the late stage of the phage lytic cycle and is required for progeny escape.
Wichuda Phothichaisri, Surang Chankhamhaengdecha, Tavan Janvilisri, Jirayu Nuadthaisong, Tanaporn Phetruen, Robert P. Fagan, Sittinan Chanarat   +6 more
doaj   +1 more source

Chitinase A, a tightly regulated virulence factor of Salmonella enterica serovar Typhimurium, is actively secreted by a Type 10 Secretion System.

PLoS Pathogens, 2023
As a facultative intracellular pathogen, Salmonella enterica serovar Typhimurium is one of the leading causes of food-borne diseases in humans. With the ingestion of fecal contaminated food or water, S. Typhimurium reaches the intestine.
Lena Krone, Larissa Faass, Martina Hauke, Christine Josenhans, Tobias Geiger   +4 more
doaj   +1 more source

Binding site‐shaped repeated sequences of bacterial wall peptidoglycan hydrolases [PDF]

FEBS Letters, 1994
The non‐catalytic C‐terminal regions of the N‐acetylmuramidase (lysozyme) of Clostridium acetobutylicum and N‐acetylmuramoyl(d‐lactyl)‐l‐alanine amidases CwlA of Bacillus subtilis, ORFL3 and CwlL of Bacillus licheniformis were previously reported to have similarities with the amino acid sequence of the non‐catalytic N‐terminal module of the ...
Ghuysen, Jean-Marie, Lamotte-Brasseur, Josette, Joris, Bernard, Shockman, Gérald D.   +3 more
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Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile

Microbial Cell, 2018
Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
doaj   +1 more source

Carbohydrate recognition and lysis by bacterial peptidoglycan hydrolases

Current Opinion in Structural Biology, 2017
The major component of bacterial cell wall is peptidoglycan (PG), a complex polymer formed by long glycan chains cross-linked by peptide stems. PG is in constant equilibrium requiring well-orchestrated coordination between synthesis and degradation. The resulting cell-wall fragments can be recycled, act as messengers for bacterial communication, as ...
Alcorlo, Martín, Martínez-Caballero, S., Molina, R., Hermoso, Juan A.   +3 more
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