Results 41 to 50 of about 20,249 (205)

Characterisation of the peptidoglycan hydrolases of Listeria monocytogenes EGD [PDF]

FEMS Microbiology Letters, 2006
The peptidoglycan hydrolase profile of Listeria monocytogenes EGD has been characterised under a variety of environmental and physiological conditions, using renaturing sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The profiles show activities ranging from 29 to 186 kDa.
A M, McLaughlan, S J, Foster
openaire   +3 more sources

Co-Catalytic Metallopeptidases as Pharmaceutical Targets [PDF]

, 2003
Understanding the reaction mechanism of co-catalytic metallopeptidases provides a starting point for the design and synthesis of new molecules that can be screened as potential pharmaceuticals. Many of the enzymes that contain co-catalytic metallo-active
Bzymek, Krzysztof P., Holz, Richard C., Swierczek, Sabina I.   +2 more
core   +2 more sources

Regulated proteolysis of a cross-link-specific peptidoglycan hydrolase contributes to bacterial morphogenesis. [PDF]

Proc Natl Acad Sci U S A, 2015
Singh SK, Parveen S, SaiSree L, Reddy M.
europepmc   +2 more sources

Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex [PDF]

, 2014
Gram-negative bacteria use the Type VI secretion system (T6SS) to inject toxic proteins into rival bacteria or eukaryotic cells. However, the mechanism of the T6SS is incompletely understood. In the present study, we investigated a conserved component of
Alan R. Prescott, Aschtgen, Aschtgen, Aschtgen, Aschtgen, Ballister, Basler, Basler, Bonemann, Bonemann, Boyer, Burtnick, Casabona, Casabona, Cascales, Coulthurst, Dong, English, Felisberto-Rodrigues, Francesca R. Cianfanelli, Fritsch, Gerlach, Grant English, Holland, Hood, Jack, Kaniga, Kapitein, Kapitein, Laue, Leiman, Leiman, Lossi, Ma, Ma, Ma, MacIntyre, Mougous, Murdoch, Olwyn Byron, Pell, Potvin, Pukatzki, Rao, Rickman, Russell, Russell, Sambrook, Sarah J. Coulthurst, Schell, Schuck, Schwarz, Shneider, Silverman, Srikannathasan, Suarez, Vistica, Whitney, Zheng, Zheng, Zoued   +60 more
core   +3 more sources

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G., Briers, Yves, Danis‐Wlodarczyk, Katarzyna, Drulis‐Kawa, Zuzanna, Jang, Ho Bin, Lavigne, Rob, Lood, Cédric, Noben, Jean‐Paul, Noort, Vera, Vandenheuvel, Dieter   +9 more
core   +1 more source

Coordinated and Distinct Roles of Peptidoglycan Carboxypeptidases DacC and DacA in Cell Growth and Shape Maintenance under Stress Conditions

Microbiology Spectrum, 2023
Peptidoglycan (PG) is an essential bacterial architecture pivotal for shape maintenance and adaptation to osmotic stress. Although PG synthesis and modification are tightly regulated under harsh environmental stresses, few related mechanisms have been ...
Umji Choi, Si Hyoung Park, Han Byeol Lee, Ji Eun Son, Chang-Ro Lee   +4 more
doaj   +1 more source

The Bifunctional Cell Wall Hydrolase CwlT Is Needed for Conjugation of the Integrative and Conjugative Element ICEBs1 in Bacillus subtilis and B. anthracis [PDF]

, 2014
The mobile genetic element ICEBs1 is an integrative and conjugative element (ICE) found in Bacillus subtilis. One of the ICEBs1 genes, cwlT, encodes a cell wall hydrolase with two catalytic domains, a muramidase and a peptidase.
DeWitt, Tyler, Grossman, Alan Davis
core   +1 more source

Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division [PDF]

, 2014
Bacterial cell division is a fundamental process that requires the coordinated actions of a number of proteins which form a complex macromolecular machine known as the divisome.
Bottomley, Amy L., Foster, Simon J., Garcia-Lara, Jorge, Hurd, Alexander F., Kabli, Azhar F., Turner, Robert D.   +5 more
core   +1 more source

Chitinase A, a tightly regulated virulence factor of Salmonella enterica serovar Typhimurium, is actively secreted by a Type 10 Secretion System.

PLoS Pathogens, 2023
As a facultative intracellular pathogen, Salmonella enterica serovar Typhimurium is one of the leading causes of food-borne diseases in humans. With the ingestion of fecal contaminated food or water, S. Typhimurium reaches the intestine.
Lena Krone, Larissa Faass, Martina Hauke, Christine Josenhans, Tobias Geiger   +4 more
doaj   +1 more source

Potential Role of the Host-Derived Cell-Wall Binding Domain of Endolysin CD16/50L as a Molecular Anchor in Preservation of Uninfected Clostridioides difficile for New Rounds of Phage Infection

Microbiology Spectrum, 2022
Endolysin is a phage-encoded cell-wall hydrolase which degrades the peptidoglycan layer of the bacterial cell wall. The enzyme is often expressed at the late stage of the phage lytic cycle and is required for progeny escape.
Wichuda Phothichaisri, Surang Chankhamhaengdecha, Tavan Janvilisri, Jirayu Nuadthaisong, Tanaporn Phetruen, Robert P. Fagan, Sittinan Chanarat   +6 more
doaj   +1 more source