Results 31 to 40 of about 12,407 (196)
Peptidoglycan hydrolase of an unusual cross-link cleavage specificity contributes to bacterial cell wall synthesis. [PDF]
Proc Natl Acad Sci U S A, 2019 Bacteria are surrounded by a protective exoskeleton, peptidoglycan (PG), a cross-linked mesh-like macromolecule consisting of glycan strands interlinked by short peptides.
Chodisetti PK, Reddy M.
europepmc +2 more sources
Genetic Evidence for Distinct Functions of Peptidoglycan Endopeptidases in Escherichia coli
Frontiers in Microbiology, 2020 Peptidoglycan (PG) is an essential component of the bacterial exoskeleton that plays a pivotal role in the maintenance of cell shape and resistance to cell lysis under high turgor pressures.
Si Hyoung Park +4 more
doaj +1 more source
eLife, 2019 We discovered that Enterococcus faecium (E. faecium), a ubiquitous commensal bacterium, and its secreted peptidoglycan hydrolase (SagA) were sufficient to enhance intestinal barrier function and pathogen tolerance, but the precise biochemical mechanism ...
Byungchul Kim +9 more
doaj +1 more source
Enterococcus peptidoglycan remodeling promotes checkpoint inhibitor immunotherapy [PDF]
, 2021 The antitumor efficacy of cancer immunotherapy can correlate with the presence of certain bacterial species within the gut microbiome. Yet, many of the molecular mechanisms that impact host response to immunotherapy remain elusive.
Jha, Jyoti K. +13 more
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Microbiology Spectrum, 2022 Vancomycin and β-lactams are clinically important antibiotics that inhibit the formation of peptidoglycan cross-links, but their binding targets are different.
Si Hyoung Park +5 more
doaj +1 more source
Peptidoglycan Hydrolases of Escherichia coli [PDF]
Microbiology and Molecular Biology Reviews, 2011 SUMMARYThe review summarizes the abundant information on the 35 identified peptidoglycan (PG) hydrolases ofEscherichia coliclassified into 12 distinct families, including mainly glycosidases, peptidases, and amidases. An attempt is also made to critically assess their functions in PG maturation, turnover, elongation, septation, and recycling as well as
openaire +2 more sources
A second endolysin gene is fully embedded in-frame with the lysA gene of mycobacteriophage Ms6. [PDF]
PLoS ONE, 2011 Mycobacteriophages are dsDNA viruses that infect mycobacterial hosts. The mycobacteriophage Ms6 accomplishes lysis by producing two cell wall hydrolytic enzymes, Lysin A (LysA) that possesses a central peptidoglycan recognition protein (PGRP) super ...
Maria João Catalão +4 more
doaj +1 more source
Two-step localization driven by peptidoglycan hydrolase in interbacterial predation. [PDF]
ISME JAbstract Mechanisms of bacterial predation are crucial for revealing microbial adaptation strategies and interaction behaviors in the environment, yet they remain poorly understood. Previously, predators were reported to localize prey via specific cues.
Song H +17 more
europepmc +4 more sources
Characterization of an OmpA-like outer membrane protein of the acidophilic iron-oxidizing bacterium, Acidithiobacillus ferrooxidans [PDF]
, 2011 An OmpA family protein (FopA) previously reported as one of the major outer membrane proteins of an acidophilic iron-oxidizing bacterium Acidithiobacillus ferrooxidans was characterized with emphasis on the modification by heat and the interaction with ...
Kamimura, Kazuo +9 more
core +1 more source
Viruses, 2021 Bacteriophage-encoded endolysins have been identified as antibacterial candidates. However, the development of endolysins as mainstream antibacterial agents first requires a comprehensive biochemical understanding. This study defines the atomic structure
Michael J. Love +5 more
doaj +1 more source