Results 51 to 60 of about 11,450 (169)

Genetic Screens Identify Additional Genes Implicated in Envelope Remodeling during the Engulfment Stage of Bacillus subtilis Sporulation

open access: yesmBio, 2022
During bacterial endospore formation, the developing spore is internalized into the mother cell through a phagocytic-like process called engulfment, which involves synthesis and hydrolysis of peptidoglycan.
Helena Chan   +11 more
doaj   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang   +3 more
wiley   +1 more source

Novel endolysin LysMP for control of Limosilactobacillus fermentum contamination in small-scale corn mash fermentation

open access: yesBiotechnology for Biofuels and Bioproducts, 2023
Background Traditional bioethanol fermentation industries are not operated under strict sterile conditions and are prone to microbial contamination.
Maulik H. Patel   +3 more
doaj   +1 more source

The role of the gut microbiome in the regulation of high‐altitude adaptation

open access: yesiMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang   +6 more
wiley   +1 more source

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li   +3 more
wiley   +1 more source

Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78Å resolution.

open access: yesPLoS ONE, 2021
Muramidases/lysozymes hydrolyse the peptidoglycan component of the bacterial cell wall. They are found in many of the glycoside hydrolase (GH) families.
Olga V Moroz   +14 more
doaj   +1 more source

O-glycosylation as a novel control mechanism of peptidoglycan hydrolase activity. [PDF]

open access: yesJ Biol Chem, 2013
Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal region rich in Ala, Ser, and Thr (AST domain), which is of low complexity and unknown function, and a C-terminal region composed of five SH3b peptidoglycan (PG) binding domains.
Rolain T   +11 more
europepmc   +7 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak   +7 more
wiley   +1 more source

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC. [PDF]

open access: yesProc Natl Acad Sci U S A, 2014
Significance During growth and division, bacterial cells partition the cell wall to daughter cells, but the “inside-out” signals that regulate peptidoglycan (PG) hydrolysis are not well understood. Our studies of mycobacterial proteins achieve in vitro reconstitution of the regulation of the PG hydrolase, RipC, by the FtsX extracellular ...
Mavrici D   +7 more
europepmc   +6 more sources

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