Results 81 to 90 of about 6,642 (186)

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Peptidomimetics as a new generation of antimicrobial agents: current progress

Infection and Drug Resistance, 2014
Patricia Méndez-Samperio Department of Immunology, National School of Biological Sciences, National Polytechnic Institute, Mexico City, Mexico Abstract: Antibiotic resistance is an increasing public health concern around the world. Rapid increase
Méndez-Samperio P
doaj  

An Ugi–Joullié Platform for Medicinally Relevant 1,4‐Dihydrobenzothiazines

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of benzothiazine derivatives was efficiently synthesized via an UJ‐2CR of a preformed imine and diverse isocyanides. The method features mild, room‐temperature conditions, broad functional‐group tolerance, and scalability, enabling rapid access to a chemically diverse library of 19 adducts with potential for further medicinal chemistry ...
Xiaofang Lei, Christina Tomza, Maria‐Aikaterini Giannakaki, Maria Gkountouva, Ioannis Olbasalis, Rafaela Maria Giappa, Constantinos C. Stoumpos, Christos Kontogiorgis, Alexander Dömling, Constantinos G. Neochoritis   +9 more
wiley   +1 more source

Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings

Antibiotics
Antimicrobial resistance is a critical global challenge in the 21st century, validating Sir Alexander Fleming’s warning about the misuse of antibiotics leading to resistant microbes.
Shyam Kumar Mishra, Tanzina Akter, Umme Laila Urmi, George Enninful, Manjulatha Sara, Jiawei Shen, Dittu Suresh, Liangjun Zheng, Elias Shiferaw Mekonen, Binod Rayamajhee, Francesco M. Labricciosa, Massimo Sartelli, Mark Willcox   +12 more
doaj   +1 more source

On-Resin Synthesis and Diversification of Macrocyclic Disulfide Bridge Peptidomimetics via Bifunctional 5-Iodo-1,4-Triazoles. [PDF]

J Org Chem
Malone MA, Shepperson OA, Simms JE, Reid AJ, Jamieson AG.   +4 more
europepmc   +1 more source

Disrupting the Undruggable: Emerging Modalities for Targeting Protein-Protein Interactions in Oncology. [PDF]

Biology (Basel)
El-Tanani M, Rabbani SA, Wali AF, El-Tanani Y, Sharma S.   +4 more
europepmc   +1 more source

Structure-Guided SOCS3 Peptidomimetics: Design and Functional Characterization. [PDF]

ACS Omega
Cugudda A, La Manna S, Bucciero C, Castellano G, Malfitano AM, Marasco D.   +5 more
europepmc   +1 more source

Nano-G_s Protein Peptidomimetics: Rational Design of Gα C-Terminus-Derived Peptides Mimicking Key Components of G_s-β₂AR Interactions. [PDF]

Angew Chem Int Ed Engl
Tran PT, Danielsen M, Tiemann JKS, Ibrahim P, Rasmussen SGF, Kubiak X, Batebi H, Gadais C, Ballet S, Hildebrand PW, Pedersen DS, Mathiesen JM.   +11 more
europepmc   +1 more source

Indole Peptidomimetics Show Potent and Selective Activity against Drug-Resistant <i>Plasmodium falciparum</i>. [PDF]

ACS Omega
Januário MAP, Valdes TA, Maluf SEC, Mendes GR, Bonatto V, Moura IMR, Mourão PS, Corrêa AG, Guido RVC.   +8 more
europepmc   +1 more source

Evidence of an activity-enhancing conformational shift in Arabidopsis thaliana plant cysteine oxidase 4 induced by binding of substrate or substrate-mimics. [PDF]

J Biol Chem
Latter R, Hintzen JCJ, Shah LMN, Gunawardana DM, Sher RM, White MD, Mecinović J, Benesch JLP, Flashman E.   +8 more
europepmc   +1 more source