Results 51 to 60 of about 6,691 (210)

Genetic dissection of the root system architecture QTLome and its relationship with early shoot development, breeding and adaptation in durum wheat

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Root system architecture (RSA), shoot architecture, and shoot‐to‐root biomass allocation are critical for optimizing crop water and nutrient capture and ultimately grain yield. Nevertheless, only a few studies adequately dissected the genetic basis of RSA and its relationship to shoot development.
Giuseppe Sciara, Matteo Bozzoli, Fabio Fiorani, Kerstin A. Nagel, Amina Ameer, Silvio Salvi, Roberto Tuberosa, Marco Maccaferri   +7 more
wiley   +1 more source

A network-based approach to identify substrate classes of bacterial glycosyltransferases [PDF]

, 2014
Background: Bacterial interactions with the environment-and/or host largely depend on the bacterial glycome. The specificities of a bacterial glycome are largely determined by glycosyltransferases (GTs), the enzymes involved in transferring sugar ...
Lebeer, Sarah, Marchal, Kathleen, Sánchez-Rodríguez, Aminael, Tytgat, Hanne LP, Vanderleyden, Jos, Winderickx, Joris   +5 more
core   +2 more sources

The Influence of Lipopolysaccharide O‐Antigen Chain Length on Biofilm Formation Capacity and Outer Membrane Proteome Shape of Salmonella Enteritidis

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Shortening of the LPS O‐antigen part is related to decreased biofilm biomass formation, which also depends on the composition of the culture medium. Physicochemical properties of bacterial cells changed with the shortening of the O‐antigen, promoting bacterial aggregation, hydrodynamic size, zeta potential, and hydrophobicity.
Eva Krzyżewska‐Dudek, Bartłomiej Dudek, Katarzyna Kapczyńska, Paweł Pasikowski, Malwina Brożyna, Justyna Paleczny, Agata Mikołajczyk‐Martinez, Adam Junka, Jacek Rybka   +8 more
wiley   +1 more source

RNA aptamers to the peptidyl transferase inhibitor chloramphenicol

Chemistry & Biology, 1997
The problem of how macromolecules adopt specific shapes to recognize small molecules in their environment is readily addressed through in vitro selections (the SELEX protocol). RNA-antibiotic interactions are particularly attractive systems for study because they provide an opportunity to expand our understanding of molecular recognition by RNA and to ...
Burke, Donald H., Hoffman, David C., Brown, Analisa, Hansen, Mark, Pardi, Arthur, Gold, Larry   +5 more
openaire   +2 more sources

Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress [PDF]

, 2017
Accumulating evidence shows that oxidative stress is involved in a wide variety of human diseases: rheumatoid arthritis, Alzheimer’s disease, Parkinson’s disease, cancers, etc.
Ahmadinejad, Fereshteh., Bidkhori, Gholamreza., Geir Møller, Simon., Hashemzadeh-Chaleshtori, Morteza., Jami, Mohammad-Saeid.   +4 more
core   +2 more sources

miR‐140‐5p Overexpression Contributes to Oxidative Stress and Mitochondrial Dysfunction in Hutchinson‐Gilford Progeria Syndrome Fibroblasts Through NRF2 Pathway

Aging Cell, Volume 24, Issue 12, December 2025.
This study identifies a novel molecular mechanism involving miR‐140‐5p that contributes to the pathogenesis of HGPS. By decreasing NRF2 expression, miR‐140‐5p overexpression results in downregulation of the NRF2/KEAP1/HO‐1 antioxidant pathway in HGPS fibroblasts, leading to increased oxidative stress and mitochondrial dysfunction, two hallmarks of ...
Léa Toury, Diane Frankel, Sara Nael, Mario Abaji, Léa Le Goff, Marie Basset, Coraline Airault, Bertrand Vernay, Elva María Novoa‐del‐Toro, Catherine Bartoli, Anaïs Baudot, Frederique Magdinier, Elise Kaspi, Patrice Roll   +13 more
wiley   +1 more source

Die molekulare Logik der nichtribosomalen Peptidsynthetasen: Identifizierung und biochemische Charakterisierung der Biosynthesegene für Gramicidin A [PDF]

, 2005
Gramicidin ist ein Polypeptid, das aus 15 hydrophoben Aminosäuren mit alternierender L-D-Konfiguration besteht. In vivo bilden sich Homodimere, die in Membranen als Ionenkanäle fungieren.
Bölker, Michael (Prof. Dr.), Schracke, Nadine   +1 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Peptidyl transferase center decompaction and structural constraints during early protein elongation on the ribosome [PDF]

, 2021
Bin Jia, Tianlong Wang, J. Lehmann
openalex   +1 more source

Proteomic analysis of skin invasion by blood fluke larvae. [PDF]

, 2008
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon, Debnath, Moumita, Hansell, Elizabeth, Ingram, Jessica, Lim, KC, McKerrow, James H, Medzihradszky, Katalin F, Sajid, Mohammed   +7 more
core   +1 more source