Results 81 to 90 of about 3,645 (164)

Peptidylarginine Deiminases: An Overview of Recent Advances in Citrullination Research

International Journal of Molecular Sciences
The peptidylarginine deiminase (PAD) family includes five isozymes (PAD1–4 and PAD6) with unique tissue distributions and substrate specificities. These enzymes facilitate citrullination, a post-translational modification where positively charged arginine residues are converted into neutral citrulline residues in the presence of calcium ions.
Magdalena Kijak-Boćkowska, Joanna Czerwińska, Agnieszka Owczarczyk-Saczonek   +2 more
openaire   +3 more sources

Ppad Carried By Omvs Exacerbated Masld Through Npas2/Cyp4a10 Pathway

International Dental Journal
Aim or purpose: This study investigated the causal link between periodontitis and metabolic dysfunction-associated steatotic liver disease (MASLD), with a specific focus on how P. gingivalis OMVs mediate hepatic lipid dysregulation through PPAD enzymatic
Yanqing Liu, Li Lin, Zhaorong Li
doaj   +1 more source

Peptidylarginine deiminase 4 and ADAMTS13 activity in Staphylococcus aureus bacteraemia. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Martens CP, Peetermans M, Vanassche T, Verhamme P, Jacquemin M, Martinod K.   +5 more
europepmc   +1 more source

Subcellular location of peptidylarginine deiminase in the mouse brain. [PDF]

Agricultural and Biological Chemistry, 1987
TAKAHARA, Hidenari, KOYAMA, Masahiko, SUGAWARA, Kiyoshi   +2 more
openaire   +2 more sources

Peptidylarginine Deiminase of the Mouse

Journal of Biological Chemistry, 1989
H Takahara, M Tsuchida, M Kusubata, K Akutsu, S Tagami, K Sugawara   +5 more
openaire   +1 more source

Peptidylarginine deiminase in Porphyromonas gingivalis-derived outer membrane vesicles exacerbates metabolic dysfunction-associated steatotic liver disease through the NPAS2/CYP4A10 pathway

Journal of Nanobiotechnology
This study investigated the relationship between periodontitis and metabolic dysfunction-associated steatotic liver disease (MASLD), with a specific focus on the role of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) carried by P.
Yanqing Liu, Xiaomeng Xue, Zhaorong Li, Ziming Ge, Muzhou Jiang, Jingbo Liu, Yaping Pan, Li Lin   +7 more
doaj   +1 more source

Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA. [PDF]

Front Immunol, 2023
Geary B, Sun B, Tilvawala RR, Barasa L, Tsoyi K, Rosas IO, Thompson PR, Ho IC.   +7 more
europepmc   +1 more source

Retracted: Effect of Peptidylarginine Deiminase 4 on Endothelial Progenitor Cell Function in Peripheral Arterial Disease. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +1 more source

Inhibition of PADI2-mediated vimentin citrullination alleviates silica-induced pulmonary fibrosis in mice

Particle and Fibre Toxicology
Silicosis remains a critical occupational health concern worldwide, lacking effective treatments due to unclear mechanisms. In this study, we investigated the citrullinated proteomic profile and its effects in mice exposed to silica.
Fuyu Jin, Yaqian Li, Tian Li, Shupeng Liu, Dingjie Xu, Heliang Liu, Zhongqiu Wei, Xuemin Gao, Na Mao, Wenchen Cai, Yiwei Shi, Haibo Zhang, Hong Xu   +12 more
doaj   +1 more source

Peptidylarginine deiminase 2 regulates expression of DGCR8 affecting miRNA biogenesis in gonadotrope cells. [PDF]

Reproduction, 2023
Ralston BA, Khan L, DeVore SB, Bronnenberg TA, Flock JW, Sequoia AO, Thompson PR, Navratil AM, Cherrington BD.   +8 more
europepmc   +1 more source