Chain-End Modifications and Sequence Arrangements of Antimicrobial Peptoids for Mediating Activity and Nano-Assembly [PDF]
Frontiers in Chemistry, 2020 Poly(N-substituted glycine) “peptoids” are an interesting class of peptidomimics that can resist proteolysis and mimic naturally found antimicrobial peptides (AMPs), which exhibit wide spectrum activity against bacteria.
Abshar Hasan +11 more
doaj +4 more sources
Ugi multicomponent reaction to prepare peptide–peptoid hybrid structures with diverse chemical functionalities [PDF]
, 2018 Monodisperse sequenced peptides and peptoids present unique nano-structures based on their self-assembled secondary and tertiary structures. However, the generation of peptide and peptoid hybrid oligomers in a sequence-defined manner via Ugi ...
Azevedo, Helena S. +12 more
core +3 more sources
Topology-Dependent Antifreeze Properties of Biomimetic Linear and Star-Shaped Peptoids [PDF]
BiomimeticsDeveloping safe and efficient cryoprotectants is critical for effective cryopreservation in biomedical applications. Inspired by natural antifreeze proteins (AFPs), a series of linear and star-shaped peptoids featuring isopropanol side chains to mimic ...
Lei Feng +7 more
doaj +2 more sources
Identification of cannabinoid-sensitive and -resistant oral bacteria [PDF]
Frontiers in MicrobiologyMarijuana, an emerging risk factor for periodontitis, contains multiple potent antibacterials, particularly the phytocannabinoids. Microbial dysbiosis is a hallmark of this destructive oral disease. We examined a panel of oral bacteria for susceptibility
David A. Scott +8 more
doaj +2 more sources
One-Pot Approach Towards Peptoids Synthesis Using 1,4-Dithiane-2,5-Diol via Multicomponent Approach and DFT-Based Computational Analysis [PDF]
MoleculesPeptoids are peptidomimetics in which the side chain is attached to the nitrogen of the amide group rather than the α-carbon. This alteration in the backbone structure is highly valued because it endows beneficial properties, including enhanced ...
Musrat Shaheen, Akbar Ali
doaj +2 more sources
Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α‑Peptoids) and Derivatives
Molecules, 2010 Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-acid monomer units) are oligomeric synthetic polymers that are becoming a valuable molecular tool in the biosciences.
Adrian S Culf
exaly +3 more sources
Advanced Science, 2020 Silicone (Si) is one type of anode materials with intriguingly high theoretical capacity. However, the severe volume change associated with the repeated lithiation and delithiation processes hampers the mechanical/electrical integrity of Si anodes and ...
Chaofeng Zhang +2 more
exaly +2 more sources
Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate [PDF]
Molbank, 2017 Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate was synthesized via Ugi four component (4C) reaction at ambient temperature. The protocol employs a reaction between formaldehyde, furfurylamine, acrylic acid, and ethyl 2-isocyanoacetate.
Shimoga D. Ganesh +3 more
doaj +3 more sources
Assembly of short amphiphilic peptoids into nanohelices with controllable supramolecular chirality [PDF]
Nature CommunicationsA long-standing challenge in bioinspired materials is to design and synthesize synthetic materials that mimic the sophisticated structures and functions of natural biomaterials, such as helical protein assemblies that are important in biological systems.
Renyu Zheng +8 more
doaj +2 more sources
Assembled peptoid crystalline nanomaterials as carbonic anhydrase mimics for promoted hydration and sequestration of CO2 [PDF]
Nature CommunicationsCarbonic anhydrase (CA) mimics have received significant attention due to their promising applications in the enhanced hydration and sequestration of CO2.
Progyateg Chakma +12 more
doaj +2 more sources