Results 31 to 40 of about 5,830 (259)
Surface-immobilised antimicrobial peptoids [PDF]
Biofouling, 2008 Surface modification techniques that create surfaces capable of killing adherent bacteria are promising solutions to infections associated with implantable medical devices. Antimicrobial (AM) peptoid oligomers (ampetoids) that were designed to mimic helical AM peptides were synthesised with a peptoid spacer chain to allow mobility and an adhesive ...
Andrea R, Statz +4 more
openaire +2 more sources
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
PLoS ONE, 2014 Cationic, amphipathic host defense peptides represent a promising group of agents to be developed for anticancer applications. Poly-N-substituted glycines, or peptoids, are a class of biostable, peptidomimetic scaffold that can display a great diversity ...
Wei Huang +6 more
doaj +1 more source
Antioxidants, 2023 Copper is an essential metal ion that is involved in critical cellular processes, but which can also exhibit toxic effects through its ability to catalyze reactive oxygen species (ROS) formation. Dysregulation of copper homeostasis has been implicated in
Anastasia Esther Behar, Galia Maayan
doaj +1 more source
Reconciling Simulations and Experiments With BICePs: A Review
Frontiers in Molecular Biosciences, 2021 Bayesian Inference of Conformational Populations (BICePs) is an algorithm developed to reconcile simulated ensembles with sparse experimental measurements.
Vincent A. Voelz +2 more
doaj +1 more source
Organic Letters, 2008 The first synthesis of functionalized -peptoid macrocycles is reported. X-ray crystallographic structure of tetramer 9 reveals a C2-symmetrical derivative with unexpected all-cis-amide bonds and spatial disposition of the appendages toward the two opposite faces of the ring. Quantum calculations suggest that 9 is locked in this layout.
Roy, Olivier +4 more
openaire +2 more sources
Triangular prism-shaped β-peptoid helices as unique biomimetic scaffolds [PDF]
, 2015 β-Peptoids are peptidomimetics based on N-alkylated β-aminopropionic acid residues (or N-alkyl-β-alanines). This type of peptide mimic has previously been incorporated in biologically active ligands and has been hypothesized to be able to exhibit ...
Fristrup, Peter +3 more
core +1 more source
100th Anniversary of Macromolecular Science Viewpoint: Opportunities in the Physics of Sequence-Defined Polymers [PDF]
, 2020 Polymer science has been driven by ever-increasing molecular complexity, as polymer synthesis expands an already-vast palette of chemical and architectural parameter space.
Perry, Sarah L., Sing, Charles E.
core +3 more sources
Frontiers in Bioscience-Landmark, 2022 Background: Antimicrobial peptides (AMPs) are short, cationic, amphipathic molecules that have gained tremendous popularity as alternatives to traditional antibiotics due to their lower propensity to develop bacterial resistance.
Bettina Simone Fleck +4 more
doaj +1 more source
Development of Peptoid-Based Ligands for the Removal of Cadmium from Biological Media. [PDF]
, 2015 Cadmium poisoning poses a serious health concern due to cadmiums increasing industrial use, yet there is currently no recommended treatment. The selective coordination of cadmium in a biological environment-i.e.
Francis, Matthew +2 more
core +2 more sources
Exploiting protected maleimides to modify oligonucleotides, peptides and peptide nucleic acids [PDF]
, 2015 This manuscript reviews the possibilities offered by 2,5-dimethylfuran-protected maleimides. Suitably derivatized building blocks incorporating the exo Diels-Alder cycloadduct can be introduced at any position of oligonucleotides, peptide nucleic acids ...
Brun Cubero, Omar +3 more
core +2 more sources