Results 61 to 70 of about 5,830 (259)
SYNTESIS AND CRYSTALLINE STRUCTURE OF THE EXO-3,6-DIMETHYL-3,6-EPOXI-1,2,3,6-TETRAHYDROPHTLALIMIDE AND ITS N-BROMODECYL ANALOG: TWO THERMALLY LABILE DIELS-ALDER ADDUCTS [PDF]
, 2014 Indexación: Web of Science; Scielo.The molecular structure of the exo-3,6-dimethyl-3,6-epoxi-1,2,3,6-tetrahydrophthalimide (1), determined by X-ray diffraction analysis, as well as, its complete spectroscopic characterization and the synthesis and ...
ARAYA-FUENTES, EYLEEN +4 more
core +2 more sources
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Structural Diversity of Peptoids: Tube-Like Structures of Macrocycles
Molecules, 2020 Peptoids, or poly-N-substituted glycines, are characterised by broad structural diversity. Compared to peptides, they are less restricted in rotation and lack backbone-derived H bonding.
Claudine Nicole Herlan +4 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus [PDF]
, 2013 BACKGROUND: The increase in antibiotic resistant bacteria has led to renewed interest in development of alternative antimicrobial compounds such as antimicrobial peptides (AMPs), either naturally-occurring or synthetically-derived.
Cohn, Marianne T +9 more
core +1 more source
Peptoid special delivery [PDF]
Science-Business eXchange, 2008 Scientists at the University of Karlsruhe have designed peptoids that deliver therapeutics to intracellular targets without any toxic effects in vitro. The technique could produce carriers that deliver drugs exclusively to specific intracellular locations—if peptoids show as much promise in vivo.
openaire +1 more source
Synthesis and Characterization of Glyco‐Decorated Silsesquioxane‐Metallosalen Complexes
ChemistrySelect, Volume 11, Issue 5, 5 February 2026.Glyco‐decorated COSS‐metallosalen complexes were synthesized and characterized. Their metal ion‐dependent D4h or S4 geometry was experimentally verified by single‐crystal X‐ray diffraction using model compounds with the same tetranuclear core. Ribonuclease activity of these complexes was studied, but it remained modest compared to other metal ion‐based
Hanni Haapsaari +4 more
wiley +1 more source
Solid-Phase Synthesis and Circular Dichroism Study of β-ABpeptoids
Molecules, 2019 The development of peptidomimetic foldamers that can form well-defined folded structures is highly desirable yet challenging. We previously reported on α-ABpeptoids, oligomers of N-alkylated β2-homoalanines and found that due to the presence ...
Ganesh A. Sable +2 more
doaj +1 more source
Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids [PDF]
, 2012 A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good ...
Grubbs, Robert H. +3 more
core +1 more source
β-Peptoid Foldamers at Last [PDF]
Accounts of Chemical Research, 2015 For a long time, peptides were considered unsuitable for drug development due to their inherently poor pharmacokinetic properties and proteolytic susceptibility. However, this paradigm has changed significantly in the past decade with the approval of numerous antibodies and proteins as drugs.
Laursen, Jonas S +2 more
openaire +3 more sources