Results 81 to 90 of about 336,728 (304)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Perceived external prestige as a mediator between quality of work life and organisational commitment of public sector employees in Ghana

SA Journal of Industrial Psychology, 2015
Orientation: Research efforts have been directed at understanding the relationship between quality of work life and organisational commitment, but these studies have not elucidated the mediating role of perceived external prestige in this relationship ...
Oluyinka Ojedokun, Erhabor S. Idemudia, Mercy Desouza   +2 more
doaj   +1 more source

Barriers to the successful exploitation of ERP systems in Chinese state-owned enterprises

, 2010
Adopting a systems perspective, the research presented in this paper aims at identifying, assessing and discussing potential cultural, organisational and system barriers to the successful exploitation of Enterprise Resource Planning (ERP) systems in the ...
Nunes, J.M.B., Peng, G.C.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The contributions of self-efficacy and perceived organisational support when taking charge at work

SA Journal of Industrial Psychology, 2012
Orientation: Taking charge as an extra role in the workplace is necessary for the survival of modern firms. Therefore, understanding the personal and organisational factors when one takes charge is critical for organisations. Research purpose: The aim of
Ike E. Onyishi, Elizabeth Ogbodo
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

HR performance within Saudi Arabian organisations : is the relationship between 'job security and ill-treatment' and job satisfaction moderated by organisational support : a thesis presented in partial fulfilment of the requirement for the degree of Master of Business Studies in Management at Massey University, Albany, New Zealand [PDF]

, 2015
HR performance, particularly employees’ performance, has been well researched in Western countries. However, many Asian countries, including the region of the Arabic Gulf, are still under-researched in relation to this subject.
Al Muhanna, Abdullah Ali Z
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Electronic information sharing in local government authorities: Factors influencing the decision-making process [PDF]

, 2013
This is the post-print version of the final paper published in International Journal of Information Management. The published article is available from the link below.
Agranoff, Akbulut, Alinaghi Ziaee Bigdeli, Anderson, Beaumaster, Belton, Buss, Cavaye, Clegg, Dawes, Denzin, Doherty, Dutta, Edwards, Faerman, Fan, Forman, Fountain, Gil-Garcia, Gil-Garcia, Gil-Garcia, Guo, Heeks, Jankowicz, Jiang, Kamal, Kamal, Kelle, Khoo, Kim, Lam, Lam, Landsbergen, Lee, Lee, Lou, Luna-Reyes, Miles, Muhammad Mustafa Kamal, Navarrete, Neergaard, Pardo, Pardo, Philip, Remenyi, Rogers, Rogers, Saaty, Salmeron, Saunders, Scholl, Senyucel, Sergio de Cesare, Tan, Themistocleous, Yin, Yin, Zahedi, Zaheer, Zheng   +59 more
core   +1 more source

Perceived Organisational Support, Work Engagement and Organisational Citizenship Behaviour of Nurses at Victoria Hospital

Journal of Psychology, 2013
This study explored the relationship between perceived organisational support, work engagement and organisational citizenship behaviour amongst nurses at the Victoria hospital in Alice, Eastern Cape, South Africa. Simple random sampling was used to draw a sample of n=106.
Dumisani Mathumbu, Nicole Dodd
openaire   +1 more source