Results 91 to 100 of about 8,010,517 (281)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Conversation Elaboration and Emotional Well-Being In Perceived Social Support [PDF]

open access: yes, 2011
Social support is an extremely diverse topic. It is the subject of approximately forty thousand scholarly articles when entered into the Grand Valley State University library database under the keyword, “social support.” For example, social support has ...
Andrews, Justin P.
core  

The contributions of self-efficacy and perceived organisational support when taking charge at work

open access: yesSA Journal of Industrial Psychology, 2012
Orientation: Taking charge as an extra role in the workplace is necessary for the survival of modern firms. Therefore, understanding the personal and organisational factors when one takes charge is critical for organisations. Research purpose: The aim of
Ike E. Onyishi, Elizabeth Ogbodo
doaj   +1 more source

Impact of Perceived Organisational Support on Organisational Citizenship Behaviour on Health Care and Cure Professionals

open access: yesManagement Dynamics, 2022
Research in Human Resource Management has proved that high growth organisations face greater challenge in HR management compared to organisations which are slow in growth. With the service sector gradually emerging as fastest growing sector, it provides challenge to the organisations providing services.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effects of perceived organisation support, employee engagement and organisation citizenship behaviour on quality performance

open access: yesTotal Quality Management & Business Excellence, 2012
The study investigated the influence of perceived organisation support, employee engagement, and organisation citizenship behaviour on quality performance of ISO 9001:2000 certified manufacturing firms in Sri Lanka. A random sample of 255 shop-floor employees that fulfilled the selection criteria set for the study responded.
Wickramasinghe, Vathsala, Perera, S.
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Perceived organisational support and organisational citizenship the moderating effect of goal internalisation

open access: yes, 2006
This study investigated different motivational sources for organisational citizenship behaviour (OCB), examining both the direct and moderating effects of perceived organisational support (POS) and goal orientation.
Knight-Turvey, Neal.   +1 more
core  

The effects of perceived organisational support on employees' affective outcomes: evidence from the hotel industry [PDF]

open access: yes, 2010
Previous studies mainly analysed the relationship between perceived organisational support and organisational commitment in a direct way. Limited studies of tourism, however, have found that job satisfaction is a mediator variable in the relationship ...
Colakoglu, Ulker   +5 more
core   +1 more source

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