Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Impact of the Service Innovativeness on Perceived Overall Service Quality, Customer Loyalty and Perceived Customer Value in Shopping Sites [PDF]
Associated with the change of lifestyle, due to reasons such as time constraints, information access, and alternatives comparison easiness, consumers prefer directed shopping on the internet. Shopping is done along with the initiation by the internet, in
Emine Senbabaoglu
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Evaluation of Brand Equity for Automobile Car Industry: Perception of Customers in Karachi
Establishment of strong brand equity is now one of the most priorities to numerous Car Automaker companies, but achieving that objective is become difficult due to the reason that the services and products of several companies are homogenous and their ...
Masood Hassan
doaj
Estudio de la invarianza de escala mediante el método de cálculo integral en la medición de la calidad percibida de los servicios deportivos. (Analysing scale invariance through integral calculus when measuring perceived quality in sports services.) [PDF]
ResumenEsta investigación presenta un nuevo método para el estudio de la invarianza de escala que complementa otros métodos existentes, lo que contribuye a realizar un análisis ecléctico y multifocal de un problema importante en la investigación de ...
José Antonio Martínez García
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Perceived quality of society [PDF]
Drawing on evidence from across Europe, this report explores new ways in which policy can support and encourage high levels of wellbeing, using data from the European Social Survey. Much of the established evidence and analysis around wellbeing is based on a single measure – life satisfaction.
Harrison, Eric +2 more
openaire
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Marketing Mix is The Only Variable to Choose Brands and Quality?
This research is to find out how the role and influence of marketing stimuli (advertising, pricing, and sales promotion) as well as the role of family and brand awareness, brand associations, perceived quality of Pepsodent toothpaste.
Umbas Krisnanto
doaj

