Results 101 to 110 of about 8,930,537 (255)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
This paper analyses the effect of brand image, perceived quality, perceived uniqueness on loyalty of customers in the mobile telecom industry. The data for this study were gathered through face-to-face questionnaires that were distributed to target ...
Nguyen Thi Thanh Huyen
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A Rasch Analysis of a Self-Perceived Change in Quality of Life Scale in Patients with Mild Stroke
A Rasch analysis was used to assess the unidimensionality and appropriateness of the scoring level of a 13-item self- perceived change in quality of life scale (CQOL) for stroke patients.
林昭宏;王文中;許清芳;盧成皆;薛漪平;謝清麟 +1 more
core
Currently, coordinated development in terms of perceived urban quality and function has become a key problem. However, there is an imbalance between the street environment and urban amenities.
Yumeng Meng +4 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Consumer´s appreciation of regional image and the perceived quality of rural tourism [PDF]
Tourists' perception of regional image is critical as regards the degree of satisfaction obtained from the overall tourism experience. The present paper analyses the ways in which a region's image is incorporated into the tourist products and the overall
Petrou, Anastasia +2 more
core
Kiatkamjorn Kusol, Pastraporn Kaewpawong School of Nursing, and the Excellence Center of Community Health Promotion, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Pastraporn Kaewpawong, School of Nursing, and the Excellence Center of ...
Kusol K, Kaewpawong P
core

