Results 121 to 130 of about 7,963,567 (288)

Burnout in Residential Support Workers: The Impact of Locus of Control and Perceived Supervisor Support

open access: yesResidential Treatment For Children & Youth
Burnout in Residential Support Workers: The Impact of Locus of Control and Perceived Supervisor ...
Tessa Benveniste   +3 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The Mediating Role of Organization Engagement on Perceived Supervisor Support and Intention to Leave (Case study: Faghihi Hospital in Shiraz) [PDF]

open access: yesJournal of Health Management & Informatics, 2019
Background- Regarding the importance of health care providers such as nurses who have always been in stressful environment, it is clearly important for the hospital administration to employ supportive behaviors and create much more supportive atmosphere ...
Mohsen Torabi   +3 more
doaj  

Haunted By Change : Exploring and explaining the influence of Perceived Organizational Support and Perceived Supervisor Support on Commitment to Change

open access: yes, 2018
The purpose of the study is to explore and explain how and why perceived support can create a sense of want to, ought to and have to change. This study investigates perceived organizational support (POS) and perceived supervisor supports (PSS) influences on the dimensions of commitment to change (C2C), affective- (AC2C), continuous- (CC2C) and ...
Brambeck, Maria Tove Helen   +1 more
openaire   +2 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Sport coaches' perception of job autonomy, perceived organisational support and perceived support by supervisor

open access: yes, 2014
One of the most important human needs, which is often overlooked, is to develop autonomy. In the context of sport coaching, fulfilling this need requires sport coaches to have control over their jobs and determine their course of behaviour. It is a need to have ownership of a situation so that a feeling of wanting to participate and contribute to an ...
Keyser, E., Surujlal, J.
openaire   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy