Results 221 to 230 of about 49,701 (247)
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Islet rejection in perforin-deficient mice: the role of perforin and Fas.
Transplantation, 1997Perforin and Fas are the two main pathways by which cytotoxic T lymphocytes (CTLs) mediate target cell lysis in vitro. The perforin pathway is predominantly used by CD8+ cells, which comprise the majority of CTLs. The Fas pathway has been demonstrated to be the principal cytolytic mechanism in CD4+ CTLs.
K R, Ahmed, T B, Guo, K K, Gaal
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Real-time visualization of perforin nanopore assembly.
Nature Nanotechnology, 2017Carl Leung +12 more
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Autoimmune Lymphoproliferative Syndrome and Perforin
New England Journal of Medicine, 2005Frédéric, Rieux-Laucat +2 more
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Perforin-A key (shaped) weapon in the immunological arsenal.
Seminars in Cell and Developmental Biology, 2017B. Spicer +4 more
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Perforin gene defects in familial hemophagocytic lymphohistiocytosis.
Science, 1999S. Stepp +12 more
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L-Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors.
International journal of pharmaceutics, 2016K. Huttunen +5 more
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