Results 11 to 20 of about 30,427 (250)
An investigation into murine pericyte shape change in response to inflammatory stimuli in vitro and in vivo [PDF]
, 2011 PhDLeukocyte transmigration through venular walls into the surrounding tissue is a crucial event during inflammatory responses. Despite increased understanding of the mechanisms associated with leukocyte migration through endothelial cells, little is ...
Proebstl, Doris
core +4 more sources
Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte-Mediated Fibrosis and Protecting Nucleus Pulposus Cells. [PDF]
Adv Sci (Weinh)The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Ma F +12 more
europepmc +2 more sources
An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]
, 2012 Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Kennedy-Lydon, T. +10 more
core +1 more source
Colorectal cancer and primary fibroblast, pericyte conditioned media
, 2022 Proteomic profiling for 200 human cytokines of conditioned media samples as follows:PM = pericyte-conditioned pericyte mediaPCM = Caco2-conditioned pericyte mediaPSM = SW480-conditioned pericyte mediaPHM = HCT116-conditioned pericyte mediaFM = fibroblast-
Nairon, K (via Mendeley Data) +1 more
core +1 more source
Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro. [PDF]
PLoS ONE, 2011 Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis in resting tissues.
Jakob Karén +5 more
doaj +1 more source
The Journal of Clinical Investigation, 2022 Pericyte-mediated capillary constriction decreases cerebral blood flow in stroke after an occluded artery is unblocked. The determinants of pericyte tone are poorly understood.
Nils Korte +9 more
doaj +1 more source
Metabolic Coordination of Pericyte Phenotypes: Therapeutic Implications
Frontiers in Cell and Developmental Biology, 2020 Pericytes are mural vascular cells found predominantly on the abluminal wall of capillaries, where they contribute to the maintenance of capillary structural integrity and vascular permeability. Generally quiescent cells in the adult, pericyte activation
Emmanuel Nwadozi +2 more
doaj +1 more source
Metabolic Stress Impairs Pericyte Response to Optogenetic Stimulation in Pancreatic Islets
Frontiers in Endocrinology, 2022 Pancreatic islets are highly vascularized micro-organs ensuring whole body glucose homeostasis. Islet vascular cells play an integral part in sustaining adequate insulin release by beta cells.
Aurélien Michau +14 more
doaj +1 more source
Molecular Neurodegeneration, 2022 Background Loss of brain capillary pericyte is involved in the pathologies and cognitive deficits in Alzheimer’s disease (AD). The role of pericyte in early stage of AD pathogenesis remains unclear.
Jun Wang +10 more
doaj +1 more source
Renal pericytes: regulators of medullary blood flow [PDF]
, 2012 Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M. +10 more
core +1 more source