Results 11 to 20 of about 29,574 (291)
Pericytes are specialized cells located in close proximity to endothelial cells within the microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls, and maintaining the integrity of the blood–brain barrier.
Pengfei Li, Hongkuan Fan
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Pericyte mechanics and mechanobiology [PDF]
ABSTRACT Pericytes are mural cells of the microvasculature, recognized by their thin processes and protruding cell body. Pericytes wrap around endothelial cells and play a central role in regulating various endothelial functions, including angiogenesis and inflammation.
Claire A. Dessalles +2 more
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Pericytes, like vascular smooth muscle cells, are perivascular cells closely associated with blood vessels throughout the body. Pericytes are necessary for vascular development and homeostasis, with particularly critical roles in the brain, where they ...
Samantha Selhorst +10 more
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The role of pericytes seems to extend beyond their known function in angiogenesis, fibrosis and wound healing, blood-brain barrier maintenance, and blood flow regulation. More and more data are currently accumulating indicating that pericytes, uniquely positioned at the interface between blood and parenchyma, secrete a large plethora of different ...
Abderahim, Gaceb, Gesine, Paul
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The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival [PDF]
The French scientist Charles Benjamin Rouget identified the pericyte nearly 140 years ago. Since that time the role of the pericyte in vascular function has been difficult to elucidate.
Bonkowski Drew +4 more
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An investigation into murine pericyte shape change in response to inflammatory stimuli in vitro and in vivo [PDF]
PhDLeukocyte transmigration through venular walls into the surrounding tissue is a crucial event during inflammatory responses. Despite increased understanding of the mechanisms associated with leukocyte migration through endothelial cells, little is ...
Proebstl, Doris
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EBF1 is expressed in pericytes and contributes to pericyte cell commitment [PDF]
AbstractEarly B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the early stage of cell maturation. Originally described during B-cell maturation, EBF1 was subsequently identified as a crucial molecule for proper cell fate commitment of mesenchymal stem cells into adipocytes ...
Pagani F. +4 more
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ABSTRACTObjectives: Cochlear pericytes are not well characterized. The aim of this study was to further advance the characterization of cochlear pericyte location and distribution, with particular focus on pericyte‐related proteins on the capillaries of the cochlear lateral wall that are functionally integral to structure, contraction, and gap junction
Xiaorui, Shi +7 more
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Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in health and disease. HSCs ensure the storage of the majority of vitamin A in a healthy body, and they represent the major source of fibrotic tissue in liver disease ...
Enis, Kostallari, Vijay H, Shah
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Pericytes in the microvasculature [PDF]
Pericytes, also known as Rouget cells or mural cells, are associated abluminally with all vascular capillaries and post-capillary venules. Differences in pericyte morphology and distribution among vascular beds suggest tissue-specific functions. Based on their location and their complement of muscle cytoskeletal proteins, pericytes have been proposed ...
K K, Hirschi, P A, D'Amore
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