Results 21 to 30 of about 29,574 (291)
An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]
, 2012 Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Kennedy-Lydon, T. +10 more
core +1 more source
Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro. [PDF]
PLoS ONE, 2011 Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis in resting tissues.
Jakob Karén +5 more
doaj +1 more source
The Journal of Clinical Investigation, 2022 Pericyte-mediated capillary constriction decreases cerebral blood flow in stroke after an occluded artery is unblocked. The determinants of pericyte tone are poorly understood.
Nils Korte +9 more
doaj +1 more source
Metabolic Stress Impairs Pericyte Response to Optogenetic Stimulation in Pancreatic Islets
Frontiers in Endocrinology, 2022 Pancreatic islets are highly vascularized micro-organs ensuring whole body glucose homeostasis. Islet vascular cells play an integral part in sustaining adequate insulin release by beta cells.
Aurélien Michau +14 more
doaj +1 more source
Molecular Neurodegeneration, 2022 Background Loss of brain capillary pericyte is involved in the pathologies and cognitive deficits in Alzheimer’s disease (AD). The role of pericyte in early stage of AD pathogenesis remains unclear.
Jun Wang +10 more
doaj +1 more source
Frontiers in Physiology, 2023 Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal surface of microvessels, where they provide structural and biochemical support. Pericytes have been implicated in numerous lung diseases including pulmonary arterial hypertension (PAH) and allergic asthma due to their ability to differentiate into scar-forming ...
Garrison, Annelise T. +3 more
openaire +1 more source
Pflügers Archiv - European Journal of Physiology, 2013 Pericytes were originally discovered more than100 years ago as contractile cells surrounding the endothelial cells of small blood vessels. Anatomists have later on strictly defined pericytes as cells sharing a basal membrane with the endothelium.
openaire +3 more sources
Renal pericytes: regulators of medullary blood flow [PDF]
, 2012 Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M. +10 more
core +1 more source
Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation. [PDF]
PLoS ONE, 2012 During inflammation polymorphonuclear neutrophils (PMNs) traverse venular walls, composed of the endothelium, pericyte sheath and vascular basement membrane.
Shijun Wang +6 more
doaj +1 more source
Pericyte morphology and function [PDF]
, 2021 The proper delivery of blood is essential for healthy neuronal function. The anatomical substrate for this precise mechanism is the neurovascular unit, which is formed by neurons, glial cells, endothelia, smooth muscle cells, and pericytes.
Alarcón Martínez, Luis +2 more
core +2 more sources