Results 111 to 120 of about 2,231 (191)

Dynamics of perineuronal net-associated plastic factors after sensory loss

, 2018
The vestibular nucleus offers a unique window into re-opening circuit plasticity for equilibrium reflexes. Following unilateral labyrinthectomy (UL) to perturb sensory inputs to the central vestibular nucleus in adult rats, we observed correction of ...
Hau, WF, Wu, LK, Ho, SN, Ma, CW, Shum, DKY, Chan, YS   +5 more
core  

The omics techniques used in perineuronal nets research

Experimental Neurology
Neurodegenerative diseases (NDs) are progressive disorders characterized by neuronal degeneration in the central nervous system (CNS), ultimately leading to neurological dysfunction. Neurodegenerative progression is often associated with structural and functional alterations in perineuronal nets (PNNs).
Sihan, Huang, Jiao, Tang, Xiao, Wu, Huan, Xu, Sihui, Li, Hongying, Li, Siyu, Zhang, Guangxin, Xie, Tingyu, Wang, Xincheng, Pan, Ahmad, Fasih, Maochun, You, Zhanqiong, Zhong, Lushuang, Xie, Qiaofeng, Wu, Shuguang, Yu   +15 more
openaire   +2 more sources

How the forebrain transitions to adulthood: developmental plasticity markers in a long-lived rodent reveal region diversity and the uniqueness of adolescence

Frontiers in Neuroscience
Maturation of the forebrain involves transitions from higher to lower levels of synaptic plasticity. The timecourse of these changes likely differs between regions, with the stabilization of some networks scaffolding the development of others.
B. Maximiliano Garduño, Patrick Hanni, Chelsea Hays, Patricia Cogram, Patricia Cogram, Nathan Insel, Nathan Insel, Xiangmin Xu, Xiangmin Xu, Xiangmin Xu   +9 more
doaj   +1 more source

The pattern of perineuronal net elements in the mediodorsal thalamus [PDF]

, 2017
Perineuronal nets (PNNs) decrease neuroplasticity, increase stability of neural systems, and are key to ending the neurodevelopmental critical period. PNNs are found throughout the brain, including the mediodorsal (MD) thalamus, a key region in cortico ...
Hossain, Nayeem Mubarak
core  

Do Perineuronal Net Elements Contribute to Pathophysiology of Spinal Muscular Atrophy? In Vitro and Transcriptomics Insights

, 2018
Spinal muscular atrophy (SMA) is one of the most common childhood onset neurodegenerative disorders in global health whereby novel biomarkers and therapeutic targets are sorely needed.
GÜR DEDEOĞLU, BALA, Oztemur-Islakoglu, Yasemin, DAYANGAÇ ERDEN, DİDEM, ERDEM ÖZDAMAR, SEVİM, Dayangac-Erden, Didem, Gur-Dedeoglu, Bala, Erdem-Ozdamar, Sevim, Eskici, Fatma Nazli   +7 more
core   +1 more source

Mossy Fibers from Adult-generated Neurons in the Dentate Gyrus More Frequently Contact Hilar Interneurons Surrounded by Intense Perineuronal Nets

, 2019
In the present study, we aimed to research whether there was any significant relationship between hippocampal adult-born neurons’ maturation and perineuronal nets in the dorsal hippocampus.
Haye, Amanda
core  

Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex

, 2007
An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that
McCrae, Paulette A., Rocco, Mary M., Kelly, Gail, Matthews, Russell T., Brumberg, Joshua C.   +4 more
core  

CAUGHT IN THE NET PERINEURONAL NETS AND COCAINE MEMORY

, 2016
Perineuronal nets (PNNs) are aggregations of extracellular matrix molecules that form net-like structures around the perimeter of a subset of neurons within the central nervous system. PNNs appear during development in an experience-dependent manner, and
Slaker, Megan
core  

Functional screening for gene trap mutants involved in perineuronal net formation.

A tissue’s cells function within the context of an extracellular matrix (ECM) of glycosylated and crosslinked proteins that provide structural support and adhesion, while also modulating intercellularcommunication.
Abbasi, Adil
core   +1 more source

A glial perspective on the extracellular matrix and perineuronal net remodeling in the central nervous system. [PDF]

Front Cell Neurosci, 2022
Tewari BP, Chaunsali L, Prim CE, Sontheimer H.   +3 more
europepmc   +1 more source