Results 121 to 130 of about 1,903 (160)

A Study on Potential Sources of Perineuronal Net-Associated Sema3A in Cerebellar Nuclei Reveals Toxicity of Non-Invasive AAV-Mediated Cre Expression in the Central Nervous System. [PDF]

Int J Mol Sci
Gimenez GA, Romijn M, van den Herik J, Meijer W, Eggers R, Hobo B, De Zeeuw CI, Canto CB, Verhaagen J, Carulli D.   +9 more
europepmc   +1 more source

The Perineuronal Net Protein Brevican Acts in Nucleus Accumbens Parvalbumin-Expressing Interneurons of Adult Mice to Regulate Excitatory Synaptic Inputs and Motivated Behaviors. [PDF]

Biol Psychiatry
Hazlett MF, Hall VL, Patel E, Halvorsen A, Calakos N, West AE.   +5 more
europepmc   +1 more source

Timing of Methamphetamine Exposure during Adolescence Differentially Influences Parvalbumin and Perineuronal Net Immunoreactivity in the Medial Prefrontal Cortex of Female, but Not Male, Rats.

Dev Neurosci
Brinks AS, Carrica LK, Tagler DJ, Gulley JM, Juraska JM.   +4 more
europepmc   +1 more source

Modifications of perineuronal nets to regulate plasticity

, 2018
openaire   +2 more sources

Perineuronal Nets and Their Role in Synaptic Homeostasis [PDF]

International Journal of Molecular Sciences, 2019
Extracellular matrix (ECM) molecules that are released by neurons and glial cells form perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose structure is still not known in detail, surround cell bodies and dendrites, which leaves free space for synapses to come into contact.
Izabela Gutowska, Magdalena Gąssowska-Dobrowolska, Dariusz Jeżewski   +2 more
exaly   +3 more sources

Releasing Addiction Memories Trapped in Perineuronal Nets [PDF]

Trends in Genetics, 2018
Drug addiction can be conceptualized at a basic level as maladaptive learning and memory. Addictive substances elicit changes in brain circuitry involved in reward, cognition, and emotional state, leading to the formation and persistence of strong drug-associated memories that lead to craving and relapse.
Wei-Yang Chen, Amy W Lasek
exaly   +3 more sources

Perineuronal Nets: Plasticity, Protection, and Therapeutic Potential

Trends in Neurosciences, 2019
The relationship between neurons and perineuronal nets (PNNs) is attracting attention as a central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround inhibitory parvalbumin interneurons, playing roles as both a regulator of synaptic plasticity and a protective barrier. PNNs have a delayed developmental trajectory and are key
Timothy Bussey, Amy Reichelt, Dominic Hare   +2 more
exaly   +5 more sources

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The Perineuronal Net: A Weapon for a Challenge

Journal of the History of the Neurosciences, 1999
Theories and data do not always fit and sometimes are sources of conflicts among scientists. This is the case of a morphological structure, the perineuronal net, which was denied on the basis of an ideological conflict between two giants of neurosciences: Camillo Golgi and Santiago Ramon y Cajal. The perineuronal net is a reticular structure enveloping
R, Spreafico, S, De Biasi, L, Vitellaro-Zuccarello   +2 more
openaire   +2 more sources

Perineuronal nets in the auditory system

Hearing Research, 2015
Perineuronal nets (PNs) are a unique and complex meshwork of specific extracellular matrix molecules that ensheath a subset of neurons in many regions of the central nervous system (CNS). PNs appear late in development and are supposed to restrict synaptic plasticity and to stabilize functional neuronal connections.
Mandy, Sonntag, Maren, Blosa, Sophie, Schmidt, Rudolf, Rübsamen, Markus, Morawski   +4 more
openaire   +2 more sources

Neurocan Contributes to Perineuronal Net Development

Neuroscience, 2020
Perineuronal nets (PNs) are matrix molecule assemblies surrounding neuronal somata, dendrites and axon initial segments in a lattice-like appearance. PN molecules are involved in many structural and physiological processes during development and in adulthood, suggesting a crucial role in normal brain function.
Sophie, Schmidt, Thomas, Arendt, Markus, Morawski, Mandy, Sonntag   +3 more
openaire   +2 more sources