Results 121 to 130 of about 1,848 (164)

Perineuronal net degradation in epilepsy [PDF]

open access: yesEpilepsia, 2015
SummaryObjectiveWe previously reported loss of perineuronal net (PN) immunohistochemical staining around parvalbumin‐positive interneurons in the hippocampus of rats after an episode of status epilepticus (SE). We hypothesized that the loss of thePNcould alter seizure susceptibility and that matrix metalloproteinases (MMPs) were candidates for ...
Elyse K Rankin-Gee   +2 more
exaly   +3 more sources

The Perineuronal Net: A Weapon for a Challenge

Journal of the History of the Neurosciences, 1999
Theories and data do not always fit and sometimes are sources of conflicts among scientists. This is the case of a morphological structure, the perineuronal net, which was denied on the basis of an ideological conflict between two giants of neurosciences: Camillo Golgi and Santiago Ramon y Cajal. The perineuronal net is a reticular structure enveloping
R, Spreafico   +2 more
openaire   +2 more sources

Perineuronal nets in the auditory system

Hearing Research, 2015
Perineuronal nets (PNs) are a unique and complex meshwork of specific extracellular matrix molecules that ensheath a subset of neurons in many regions of the central nervous system (CNS). PNs appear late in development and are supposed to restrict synaptic plasticity and to stabilize functional neuronal connections.
Mandy, Sonntag   +4 more
openaire   +2 more sources

Neurocan Contributes to Perineuronal Net Development

Neuroscience, 2020
Perineuronal nets (PNs) are matrix molecule assemblies surrounding neuronal somata, dendrites and axon initial segments in a lattice-like appearance. PN molecules are involved in many structural and physiological processes during development and in adulthood, suggesting a crucial role in normal brain function.
Sophie, Schmidt   +3 more
openaire   +2 more sources

Perineuronal nets: past and present

Trends in Neurosciences, 1998
Golgi ranked the peripheral reticulum--which adheres intimately to nerve cell surfaces--alongside the intracellular reticulum, or Golgi apparatus,which immortalized his name. At first dismissed as an artefact of capricious staining techniques, this peripheral reticulum, or perineuronal net, is now recognized as a genuine entity in neurocytology.
Celio MR   +3 more
openaire   +3 more sources

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