Scientific Reports, 2017 The purpose of this study is to conduct modeling and simulation to understand the effect of shock-induced mechanical loading, in the form of cavitation bubble collapse, on damage to the brain’s perineuronal nets (PNNs).
Yuan-Ting Wu, Ashfaq Adnan
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Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones [PDF]
, 2018 Perineuronal nets (PNNs) are extracellular matrix structures surrounding neuronal sub-populations throughout the central nervous system, regulating plasticity.
Asher +4 more
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Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties
Cell Reports, 2019 Summary: Dendritic spines control synaptic transmission and plasticity by augmenting post-synaptic potentials and providing biochemical compartmentalization.
Angelica Foggetti +4 more
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Enriched housing enhances recovery of limb placement ability and reduces aggrecan-containing perineuronal nets in the rat somatosensory cortex after experimental stroke. [PDF]
PLoS ONE, 2014 Stroke causes life long disabilities where few therapeutic options are available. Using electrical and magnetic stimulation of the brain and physical rehabilitation, recovery of brain function can be enhanced even late after stroke. Animal models support
Alexandre Madinier +4 more
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Chondroitin sulfates and their binding molecules in the central nervous system [PDF]
, 2017 Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a ...
Djerbal, L, Kwok, JCF, Lortat-Jacob, H
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Responses in fast-spiking interneuron firing rates to parameter variations associated with degradation of perineuronal nets [PDF]
, 2023 publishedVersio
Einevoll, Gaute +6 more
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Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia. [PDF]
, 2017 Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization.
A A Grace +128 more
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Cocaine-induced plasticity in the cerebellum of sensitised mice [PDF]
, 2015 Rationale Prior research has accumulated a substantial amount of evidence on the ability of cocaine to produce short- and long-lasting molecular and structural plasticity in the corticostriatal-limbic circuitry. However, traditionally, the cerebellum
Carbó Gas, María +8 more
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Fast oscillatory activity in the anterior cingulate cortex: dopaminergic modulation and effect of perineuronal net loss. [PDF]
, 2014 Dopamine release in the prefrontal cortex plays a critical role in cognitive function such as working memory, attention and planning. Dopamine exerts complex modulation on excitability of pyramidal neurons and interneurons, and regulates excitatory and ...
Cabungcal, J.H. +3 more
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Consumption of a High-Fat Diet Alters Perineuronal Nets in the Prefrontal Cortex
Neural Plasticity, 2018 A key factor in the development of obesity is the overconsumption of fatty foods, which, in addition to facilitating weight gain, alters neuronal structures within brain reward circuitry.
P. M. Dingess +6 more
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