Results 31 to 40 of about 1,449 (148)

Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory

Cell Reports, 2019
Summary: Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly understood.
Soledad Domínguez, Christophe Clément Rey, Ludivine Therreau, Aurélien Fanton, Dominique Massotte, Laure Verret, Rebecca Ann Piskorowski, Vivien Chevaleyre   +7 more
doaj   +1 more source

Effect of Shock-Induced Cavitation Bubble Collapse on the damage in the Simulated Perineuronal Net of the Brain

Scientific Reports, 2017
The purpose of this study is to conduct modeling and simulation to understand the effect of shock-induced mechanical loading, in the form of cavitation bubble collapse, on damage to the brain’s perineuronal nets (PNNs).
Yuan-Ting Wu, Ashfaq Adnan
doaj   +1 more source

Region-Specific Alterations of Perineuronal Net Expression in Postmortem Autism Brain Tissue

Frontiers in Molecular Neuroscience, 2022
Genetic variance in autism spectrum disorder (ASD) is often associated with mechanisms that broadly fall into the category of neuroplasticity. Parvalbumin positive neurons and their surrounding perineuronal nets (PNNs) are important factors in critical ...
Cheryl Brandenburg, Cheryl Brandenburg, Gene J. Blatt   +2 more
doaj   +1 more source

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia. [PDF]

, 2017
Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization.
A A Grace, A Gokhale, A Kulak, A Reif, A-S LaMantia, AJ Sharp, AR Santos, AW Johnson, B Rodriguez-Santiago, B Zikopoulos, C Bernard, C Kaur, C Le Magueresse, CA Cea-Del Rio, CL Beasley, CZ Wang, D Mehta, DA Lewis, DA Rossignol, DJ Lodge, DT Balu, DW Meechan, E Rees, EK Lucas, F Donato, F Filice, F Fonnum, F Longordo, G Cellot, G Modinos, GC Carlson, GE Hardingham, GS Tomassy, H Hu, H Lin, H Morishita, H Morishita, H Morishita, H Stefansson, HA Fachim, HC Brenhouse, HE Stevens, I Garate, J Coyle, J Egea, J Flatow, J Hirrlinger, J Rossier, J-H Cabungcal, JB Savitz, JC Kwok, JH Cabungcal, JH Cabungcal, JH Cabungcal, JH Cabungcal, JK Yao, JM Boyce-Rustay, JM Long, JM Yang, JM Yang, JP Debost, JW Young, K Fejgin, K Gill, K Munkholm, K Q Do, K Sakimura, KQ Do, KQ Do, L Lindemann, L Xin, LJ Kobrynski, LS Callahan, M Cuenod, M Didriksen, M Inan, M Inan, M Komitova, M Puhl, M Tosic, M Yanagi, MA Benneyworth, MJ Gandal, MM Behrens, MM Behrens, MW Pitts, N Brunetti-Pierri, N Gass, N Gogolla, NC Brown, O Akyol, O Kann, O Penagarikano, O Penagarikano, O Yizhar, P Fazzari, P Gravina, P O'Donnell, P O'Donnell, P Steullet, P Steullet, P Steullet, PB Walter, PJ Uhlhaas, R Gysin, S Ben-Shachar, S Giovanoli, S Giovanoli, S Schiavone, SA Mauney, SB Powell, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SK Natarajan, SM Purcell, SY Kim, T Hikida, T K Hensch, T M Maynard, T Sakai, T Stojkovic, T Vaessen, The Dutch-Belgian Fragile X Consortium, TM Maynard, U Meyer, U Meyer, V Labrie, Y Goldshmit, Y Zhang, Z Jiang   +128 more
core   +2 more sources

Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones [PDF]

, 2018
Perineuronal nets (PNNs) are extracellular matrix structures surrounding neuronal sub-populations throughout the central nervous system, regulating plasticity.
Asher, Jessica Kwok, Matthews, Mullen, Sian Irvine   +4 more
core   +2 more sources

Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties

Cell Reports, 2019
Summary: Dendritic spines control synaptic transmission and plasticity by augmenting post-synaptic potentials and providing biochemical compartmentalization.
Angelica Foggetti, Gilda Baccini, Philipp Arnold, Thomas Schiffelholz, Peer Wulff   +4 more
doaj   +1 more source

Enriched housing enhances recovery of limb placement ability and reduces aggrecan-containing perineuronal nets in the rat somatosensory cortex after experimental stroke. [PDF]

PLoS ONE, 2014
Stroke causes life long disabilities where few therapeutic options are available. Using electrical and magnetic stimulation of the brain and physical rehabilitation, recovery of brain function can be enhanced even late after stroke. Animal models support
Alexandre Madinier, Miriana Jlenia Quattromani, Carin Sjölund, Karsten Ruscher, Tadeusz Wieloch   +4 more
doaj   +1 more source

Cocaine-induced plasticity in the cerebellum of sensitised mice [PDF]

, 2015
Rationale Prior research has accumulated a substantial amount of evidence on the ability of cocaine to produce short- and long-lasting molecular and structural plasticity in the corticostriatal-limbic circuitry. However, traditionally, the cerebellum
Carbó Gas, María, Carulli, Daniela, Cerezo García, Miguel, Gil-Miravet, Isis, Leto, Ketty, MIQUEL, MARTA, Rossi, Ferdinando, Sanchis-Segura, Carla, Vázquez Sanromán, Dolores   +8 more
core   +1 more source

Maturation of Micturition-Related Neural Circuits That Control Pelvic Visceromotor Functions in Postnatal Rats. [PDF]

Eur J Neurosci
Coordinated postnatal emergence of CRH‐ergic innervation (red) and perineuronal nets (green) in spinal micturition centers (blue) defines a sexually dimorphic timeline of circuit stabilization, highlighting a critical period for hormonally regulated visceromotor maturation (see manuscript). ABSTRACT Pelvic visceromotor functions such as micturition are
Nitabara A, Banjo Y, Takiguchi M, Funakoshi K.   +3 more
europepmc   +2 more sources

Chondroitin sulfates and their binding molecules in the central nervous system [PDF]

, 2017
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a ...
Djerbal, L, Kwok, JCF, Lortat-Jacob, H
core   +3 more sources