Results 31 to 40 of about 12,081 (284)

Comparative evaluation of the isolation and quantification of stem cells derived from dental pulp and periodontal ligament of a permanent tooth and to assess their viability and proliferation on a platelet-rich fibrin scaffold

Journal of Indian Society of Periodontology, 2017
Background: The present study aims to comparatively evaluate the isolation and quantification of stem cells derived from dental pulp and periodontal ligament of a permanent tooth and to assess their viability and proliferation on a platelet-rich fibrin ...
Rohit Khurana, Praveen Bhasker Kudva, Syed Yawer Husain   +2 more
doaj   +1 more source

TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2

Frontiers in Cell and Developmental Biology, 2021
Bone regeneration is the ultimate goal of periodontal therapies, in which osteogenic differentiation of human periodontal ligament stem cells plays a critical role.
Yi Zhao, Qiaoli Zhai, Hong Liu, Xun Xi, Shuai Chen, Dongxu Liu   +5 more
doaj   +1 more source

Periodontal ligament stem cells regulate apoptosis of neutrophils

Open Medicine, 2017
AbstractPeriodontal ligament stem cells (PDLSCs) are promising cell resource for the cell-based therapy for periodontitis and regeneration of bio-root. In this study, we investigated the effect of PDLSCs on neutrophil, a critical constituent of innate immunity, and the underlying mechanisms.
Wang Qing, Ding Gang, Xu Xin
openaire   +3 more sources

Tooth for a tooth: Tissue engineering made easy at dental chairside

Journal of Indian Society of Periodontology, 2017
Background: Stem cells are unspecialized, multipotent cells which can differentiate into different cell types. The human periodontal ligament encloses subpopulation of Periodontal Ligament Stem Cells (PDLSCs) which are able to regenerate the periodontium
Vandana Kharidhi Laxman, Rajendra Gururao Desai   +1 more
doaj   +1 more source

Efficacy of Periodontal Stem Cell Transplantation in the Treatment of Advanced Periodontitis

Cell Transplantation, 2011
Periodontitis is the most common cause for tooth loss in adults and advanced types affect 10–15% of adults worldwide. The attempts to save tooth and regenerate the periodontal apparatus including cementum, periodontal ligament, and alveolar bone reach to
Joo-Young Park, Soung Hoo Jeon, Pill-Hoon Choung D.D.S., Ph.D.   +2 more
doaj   +1 more source

The Effect of PDLSCs on Orthodontic Tooth Movement – A Review

Indonesian Journal of Dental Medicine, 2023
Background: Stem cells have been widely used in various fields of the health sector, one of which is dental health. Teeth with malocclusion require orthodontic treatment to achieve good function and aesthetics. Orthodontic tooth movement (OTM) occurs due
Yuliati Yuliati, Indah Listiana Kriswandini, Olivia Halim   +2 more
doaj   +1 more source

A hierarchical bilayer architecture for complex tissue regeneration

Bioactive Materials, 2022
Engineering a complete, physiologically functional, periodontal complex structure remains a great clinical challenge due to the highly hierarchical architecture of the periodontium and coordinated regulation of multiple growth factors required to induce ...
Min Yu, Dan Luo, Jing Qiao, Jiusi Guo, Danqing He, Shanshan Jin, Lin Tang, Yu Wang, Xin Shi, Jing Mao, Shengjie Cui, Yu Fu, Zixin Li, Dawei Liu, Ting Zhang, Chi Zhang, Zhou Li, Yongsheng Zhou, Yan Liu   +18 more
doaj   +1 more source

Periodontal ligament stem cell: An update

Journal of Advanced Clinical and Research Insights, 2014
The periodontium is a complex of four tissues of which two are hard and rests are soft. The hard tissue being the alveolar bone and the cementum and soft tissue consists of the periodontal ligament and the gingiva. Periodontitis is multifactorial infectious disease of the supporting structures of the teeth, characterized by destruction of the bone and ...
Avikal Jain, Ashish Agarwal, Shankar T. Gokhale, R. G. Shiva Manjunath, Neha Mishra   +4 more
openaire   +1 more source

Periodontal Ligament Stem Cell-Mediated Treatment for Periodontitis in Miniature Swine [PDF]

Stem Cells, 2008
AbstractPeriodontitis is a periodontal tissue infectious disease and the most common cause for tooth loss in adults. It has been linked to many systemic disorders, such as coronary artery disease, stroke, and diabetes. At present, there is no ideal therapeutic approach to cure periodontitis and achieve optimal periodontal tissue regeneration.
Liu, Y., Zheng, Y., Ding, G., Fang, D., Zhang, C., Bartold, P., Gronthos, S., Shi, S., Wang, S.   +8 more
openaire   +4 more sources

MEST Regulates the Stemness of Human Periodontal Ligament Stem Cells

Stem Cells International, 2020
Periodontal ligament (PDL) stem cells (PDLSCs) have been reported as a useful cell source for periodontal tissue regeneration. However, one of the issues is the difficulty of obtaining a sufficient number of PDLSCs for clinical application because very few PDLSCs can be isolated from PDL tissue of donors.
Daigaku Hasegawa, Kana Hasegawa, Hiroshi Kaneko, Shinichiro Yoshida, Hiromi Mitarai, Mai Arima, Atsushi Tomokiyo, Sayuri Hamano, Hideki Sugii, Naohisa Wada, Tamotsu Kiyoshima, Hidefumi Maeda   +11 more
openaire   +3 more sources