Results 31 to 40 of about 118,363 (344)

The potential of Antheraea pernyi silk for spinal cord repair [PDF]

, 2017
This work was supported by the Institute of Medical Sciences of the University of Aberdeen, Scottish Rugby Union and RS McDonald Charitable Trust. We are grateful to Mr Nicholas Hawkins from Oxford University and Ms Annette Raffan from the University of ...
Huang, W, Knight, D, Lesage, S, Rajnicek, A M, Varone, A, Vollrath, F   +5 more
core   +2 more sources

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila, Chernov, Andrei V, Dolkas, Jennifer, Hullugundi, Swathi K, Remacle, Albert G, Shubayev, Veronica I, Strongin, Alex Y   +6 more
core   +2 more sources

Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway

iScience
Summary: Fibrotic scar is one of the main impediments to axon regeneration following spinal cord injury (SCI). In this study, we found that CD44 was upregulated during the formation of fibrotic scar, and blocking CD44 by IM7 caused downregulation of ...
Jin Guo, Tuo Yang, Weizhong Zhang, Kaiming Yu, Xiong Xu, Weizhen Li, Lili Song, Xiaosong Gu, Rangjuan Cao, Shusen Cui   +9 more
doaj   +1 more source

ATP Released by Injured Neurons Activates Schwann Cells [PDF]

, 2016
Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco, Cesare eMontecucco, Elisa eDuregotti, Elisanna eBergamin, Kees eJalink, Michela eRigoni, Michele eScorzeto, Samuele eNegro, Umberto eRodella   +8 more
core   +2 more sources

Beta secretase activity in peripheral nerve regeneration

Neural Regeneration Research, 2017
While the peripheral nervous system has the capacity to regenerate following a nerve injury, it is often at a slow rate and results in unsatisfactory recovery, leaving patients with reduced function.
Carolyn Tallon, Mohamed H Farah
doaj   +1 more source

Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons [PDF]

, 2006
Background: Inflammation around cell bodies of primary sensory neurons and retinal ganglion cells enhances expression of neuronal growth-associated genes and stimulates axonal regeneration.
Anderson, PN, Hossain-Ibrahim, MK, Lieberman, AR, MacNally, JK, Mason, MRJ, Rezajooi, K   +5 more
core   +2 more sources

Application and underlying mechanism of acupuncture for the nerve repair after peripheral nerve injury: remodeling of nerve system

Frontiers in Cellular Neuroscience, 2023
Peripheral nerve injury (PNI) is a structural event with harmful consequences worldwide. Due to the limited intrinsic regenerative capacity of the peripheral nerve in adults, neural restoration after PNI is difficult.
Yongke Yang, Chang Rao, Tianlong Yin, Shaokang Wang, Huiyan Shi, Huiyan Shi, Xin Yan, Lili Zhang, Xianggang Meng, Wenlong Gu, Yuzheng Du, Feng Hong   +11 more
doaj   +1 more source

The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice [PDF]

, 2013
Gangliosides are glycosphingolipids highly enriched in neural plasma membranes, where they mediate a diverse range of functions and can act as targets for auto-antibodies present in human immune-mediated neuropathy sera.
Cunningham, Madeleine E., Furukawa, Koichi, Rupp, Angie, Willison, Hugh J., Yao, Denggao   +4 more
core   +1 more source

Autophagy-targeting modulation to promote peripheral nerve regeneration

Neural Regeneration Research
Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular mechanisms.
Yan Chen, Hongxia Deng, Nannan Zhang
doaj   +1 more source

Effect of Local and Systemic Dimethylsulfoxide on Peripheral Nerve Repair: A Controlled Randomized Experimental Study

Journal of Investigative Surgery, 2021
Introduction We investigated the possible beneficial effect of dimethylsulfoxide (DMSO) on peripheral nerve repair in rats. Methods: Seventy rats were divided into four groups: control, sham, DMSO-L, and DMSO-IP. Except in the control group, nerve repair
Elif Sanli, Gungor Cagdas Dincel, Ebru Umay   +2 more
doaj   +1 more source