Results 31 to 40 of about 148,079 (169)

Peripheral Nerve Injuries and Regeneration

open access: yesAhi Evran Medical Journal, 2022
Peripheral nerves are a system consisting of various nerve fibers named according to the functions they stimulate in the target organ that provides motor and sensory stimulation between the central nervous system and peripheral organs. Peripheral nerves,
İşınsu ALKAN   +2 more
doaj   +1 more source

Growth factors-based therapeutic strategies and their underlying signaling mechanisms for peripheral nerve regeneration

open access: yesActa Pharmacologica Sinica, 2020
Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result in a significant loss of sensory or motor function. Restoration of the injured nerves requires a complex cellular and molecular response to rebuild the functional
Rui Li   +5 more
semanticscholar   +1 more source

Graphene promotes axon elongation through local stall of Nerve Growth Factor signaling endosomes [PDF]

open access: yes, 2020
Several works reported increased differentiation of neuronal cells grown on graphene; however, the molecular mechanism driving axon elongation on this material has remained elusive. Here, we study the axonal transport of nerve growth factor (NGF), the neurotrophin supporting development of peripheral neurons, as a key player in the time course of ...
arxiv   +1 more source

Mesenchymal stem cell treatment for peripheral nerve injury: a narrative review

open access: yesNeural Regeneration Research, 2021
Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life. The peripheral nervous system has an inherent capability to regenerate axons.
Rui-Cheng Zhang   +8 more
doaj   +1 more source

Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]

open access: yesarXiv, 2022
Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv  

Application of stem cells in peripheral nerve regeneration

open access: yesBurns & Trauma, 2020
Traumatic peripheral nerve injury is a worldwide clinical issue with high morbidity. The severity of peripheral nerve injury can be classified as neurapraxia, axonotmesis or neurotmesis, according to Seddon’s classification, or five different degrees ...
Sheng Yi   +6 more
semanticscholar   +1 more source

Application and underlying mechanism of acupuncture for the nerve repair after peripheral nerve injury: remodeling of nerve system

open access: yesFrontiers in Cellular Neuroscience, 2023
Peripheral nerve injury (PNI) is a structural event with harmful consequences worldwide. Due to the limited intrinsic regenerative capacity of the peripheral nerve in adults, neural restoration after PNI is difficult.
Yongke Yang   +11 more
doaj   +1 more source

Dose-effect relationship and molecular mechanism by which BMSC-derived exosomes promote peripheral nerve regeneration after crush injury

open access: yesStem cell research & therapeutics, 2020
The development of new treatment strategies to improve peripheral nerve repair after injury, especially those that accelerate axonal nerve regeneration, is very important.
Jiuhong Zhao   +20 more
semanticscholar   +1 more source

Beta secretase activity in peripheral nerve regeneration

open access: yesNeural Regeneration Research, 2017
While the peripheral nervous system has the capacity to regenerate following a nerve injury, it is often at a slow rate and results in unsatisfactory recovery, leaving patients with reduced function.
Carolyn Tallon, Mohamed H Farah
doaj   +1 more source

Drive and measurement electrode patterns for electrode impedance tomography (EIT) imaging of neural activity in peripheral nerve [PDF]

open access: yesHope, J., Vanholsbeeck, F., & McDaid, A. (2018). Drive and measurement electrode patterns for electrode impedance tomography (EIT) imaging of neural activity in peripheral nerve. Biomedical Physics and Engineering Express, 4 (6), 2018
Objective: To establish the performance of several drive and measurement patterns in EIT imaging of neural activity in peripheral nerve, which involves large impedance change in the nerve's anisotropic length axis. Approach: Eight drive and measurement electrode patterns are compared using a finite element (FE) four cylindrical shell model of a ...
arxiv   +1 more source

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