Results 121 to 130 of about 46,487 (267)

Elucidating the protective role of quercetin against lipopolysaccharide-induced necroptosis in broiler thymus: insights from Nrf2/PERK signaling based on network pharmacology and experimental validation. [PDF]

Redox Rep
Xia Y, Xie R, Huo X, Chen K, Li S, Xu S, Li S.   +6 more
europepmc   +1 more source

IGF-1 Stereotaxic Injection Induces BDNF Expression After Bilateral Common Carotid Artery Occlusion. [PDF]

In Vivo
Park J, Hwang H, Shin H, Chung Y, Kim D, Jun Y.   +5 more
europepmc   +1 more source

David Perk [PDF]

Psychiatric Bulletin, 1995
openaire   +1 more source

Measuring Lead Userness: Development and Validation of a Hierarchical Scale

Creativity and Innovation Management, Volume 34, Issue 4, Page 944-962, December 2025.
ABSTRACT Lead user theory has gained traction in both academia and practice, given that involving lead users (LUs) can yield more innovative and commercially successful products. Yet, measurement inconsistencies have hindered consensus on how to reliably assess lead userness.
Moritz Paulus, Slawka Jordanow, Sven Heidenreich, Franziska Janz   +3 more
wiley   +1 more source

Genomic insights into the tunicamycin-induced endoplasmic reticulum stress response in peripheral blood mononuclear cells: A comprehensive RNA sequencing analysis. [PDF]

Biochem Biophys Rep
Mahl LS, Meyer AH.
europepmc   +1 more source

MAPK Inhibitor‐Tolerant Persister Cells in Melanoma: Mechanisms and Therapeutic Vulnerabilities

Cancer Science, EarlyView.
Melanoma response to MAPK inhibition progresses from drug‐sensitive cells to drug‐tolerant persister states, which enable survival through adaptive signaling, metabolic rewiring, and phenotypic plasticity. These persister cells serve as an intermediate reservoir from which resistant tumors ultimately emerge. ABSTRACT Though major advancements have been
Bhoomi Shah, Mackenzie M. Mayhew, Jacob Sellers, Russell G. Witt   +3 more
wiley   +1 more source

Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling. [PDF]

Cell Rep Med
Liu J, Li M, Huang J, Xia Y, Jiang G, Zhang H, Yang J, Jiang M, Liu Y, Luo Y, Wang L, Zhang S.   +11 more
europepmc   +1 more source

Afatinib Overcomes Osimertinib Resistance via Egfr V804F Mutation in a Syngeneic Egfr‐Mutant Lung Cancer Mouse Model

Cancer Science, EarlyView.
Using an immunocompetent mouse model of Egfr Ex19del‐driven lung cancer, we found that osimertinib‐resistant tumors acquired Egfr V804F, the murine counterpart of human EGFR V802F. Afatinib, but not osimertinib, suppressed phosphorylation of EGFR and overcame V804F‐mediated resistance, providing a preclinical rationale for biomarker‐guided therapy ...
Takaaki Tanaka, Masato Fujitani, Masataka Taoka, Iwao Shimomura, Sachi Okawa, Shunta Mori, Tadahiro Kuribayashi, Jun Nishimura, Tomoka Nishimura, Ayako Morita, Naofumi Hara, Kiichiro Ninomiya, Go Makimoto, Hisao Higo, Kammei Rai, Eiki Ichihara, Shuta Tomida, Katsuyuki Hotta, Yosuke Togashi, Yoshinobu Maeda, Katsuyuki Kiura, Ryohei Katayama, Kadoaki Ohashi   +22 more
wiley   +1 more source

Exercise Exerts Antidepressant Effects via Endoplasmic Reticulum Stress Modulation: Molecular Mechanisms and Research Progress. [PDF]

Biology (Basel)
Zhou XY, Liu YW, Zhong CH, Xu R, Guan K, Li HN, Huang JT, Xue K, Wang Y, Chen XH.   +9 more
europepmc   +1 more source

Learning to Evaluate Yourself. The Consequences of Institutionalized Understandings of Progression for Young People With Care Experience

Child &Family Social Work, EarlyView.
ABSTRACT This article examines how young people who have been closely involved with child welfare services throughout their upbringing are required to assess and evaluate their life and progress in institutionalized ways. Within Danish child welfare policy and social work practice, progress is institutionally understood as a linear and one‐dimensional ...
Anne‐Kirstine Mølholt, Tea Torbenfeldt Bengtsson   +1 more
wiley   +1 more source