Results 171 to 180 of about 358,024 (354)

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Oxidative Stress and Its Role in Vascular Damage and Atherosclerosis. [PDF]

Int J Mol Sci
Pozo Giráldez A, Bravo Gómez A, Calmarza P, Sienes Bailo P, Dayaldasani Khialani A, Montolio Breva S, Sainz-Pastor N, Fort Gallifa I.   +7 more
europepmc   +1 more source

Relationships between periodontal inflammation, lipid peroxide and oxidative damage of multiple organs in rats

, 2011
Takaaki Tomofuji, Daisuke Ekuni, Koichiro Irie, Tetsuji Azuma, Naofumi Tamaki, Takayuki Maruyama, Tatsuo Yamamoto, Tatsuo Watanabe, Manabu Morita   +8 more
openalex   +2 more sources

LIPID PEROXIDATION AND OXIDATIVE PROTEIN PRODUCTS IN CHILDREN WITH EPISODIC FEVER OF UNKNOWN ORIGIN / LIPIDNA PEROKSIDACIJA I OKSIDATIVNI PROTEINSKI PRODUKTI KOD DECE SA EPIZODINOM GROZNICOM NEPOZNATOG UZROKA [PDF]

, 2013
Jelena Radović, Jelena Vojinović, Vladmila Bojanić, Tatjana Jevtović−Stoimenov, Gordana Kocićs, Maja Milojković, Andrej Veljković, Ivana Marković, Svetlana Stojanović, Dušica Pavlović   +9 more
openalex   +1 more source

The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium.

Journal of Clinical Investigation, 1996
S. Devaraj, Dai Li, I. Jialal
semanticscholar   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Fraction I of Whey Protein Hydrolysates Improves Lipid Stability and Water Retention in Ground Pork During Freeze-Thaw Cycles. [PDF]

Foods
Yin Y, Yin Y, Li J, Lv H, Tang X, Wang C, Dong Q.   +6 more
europepmc   +1 more source

Biochemical Basis in the Pathogenesis of Cataracts: A Systematic Review of Oxidative Stress, Protein Aggregation, Lipid Peroxidation, and DNA Damage

Avinash Namdeo Jadhao, Kranti Santosh Sorte Gawali, Trupti D. Ramteke   +2 more
openalex   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

<i>Chaetopterus</i> Luciferase: A Promising Tool for Online Lipid Peroxidation Detection. [PDF]

Int J Mol Sci
Shcheglov AS, Purtov KV, Zagitova RI, Kozhemyako VB, Tsarkova AS, Pepoyan A, Yampolsky IV.   +6 more
europepmc   +1 more source