Results 41 to 50 of about 184,353 (290)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Validating student score inferences using person fit statistic and verbal reports: A person-fit study for cognitive diagnostic assessment

open access: yes, 2013
The goal of this study was to investigate the usefulness of person-fit analysis in validating student score inferences in a cognitive diagnostic assessment. In this study, a two-stage procedure was used to evaluate person fit for a diagnostic test in the
Roduta Roberts, Mary, Cui, Ying
core   +2 more sources

Effects of reciprocal, perceived person–environment fit, and emotional labor on job involvement: Moderated mediation analyses

open access: yesCogent Business & Management, 2019
Purpose This study examines the relationship between emotional labor and job involvement with convenience store employee, as well as mediating (perceived P–E fit) and moderating (reciprocal P–E fit) variables of this relation by proposing a moderated ...
Ping-Fu Hsu, Shih-Kai Lin
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Person–Environment Fit and Expatriate Job Satisfaction

open access: yesThunderbird International Business Review, 2017
Despite the prominence of cross‐cultural adjustment in expatriate research, recent literature has criticized the theoretical foundation and dimensionality of this construct. Building on person–environment fit theory, we empirically investigate a multidimensional conceptualization of cross‐cultural adjustment in the work domain, considering expatriate ...
Sebastian Stoermer   +3 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Person-environment fit theory in built environment: a scoping review

open access: yesJournal of Asian Architecture and Building Engineering
Person-Environment Fit (P-E Fit) theory is an important concept for studying the complex relationships between people and the environment and for explaining individual behaviors.
Zhehan Zhang   +6 more
doaj   +1 more source

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